Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 10/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4171024 | 0.86 | CCR1 (0.51) | CCR1GFERKMT2AMEN1LMNA | |
| SCHEMBL2723108 | 0.86 | ALK (0.53) | CCR1GFERKMT2AMEN1LMNA | |
| SCHEMBL16693936 | 0.85 | CCR1 (0.53) | CCR1GFERKMT2AMEN1LMNA | |
| SCHEMBL13362063 | 0.85 | MAPT (0.58) | CCR1GFERKMT2AMEN1LMNA | |
| SCHEMBL4172479 | 0.84 | ALK (0.50) | CCR1GFERLMNAMAPTALDH1A1 | |
| SCHEMBL3128279 | 0.83 | CCR1 (0.51) | CCR1GFERKMT2AMEN1LMNA | |
| SCHEMBL15650773 | 0.83 | CCR1 (0.48) | CCR1GFERKMT2AMEN1LMNA | |
| SCHEMBL2205957 | 0.82 | CASP6 (0.59) | GFERKMT2AMEN1LMNAMAPT | |
| SCHEMBL13362096 | 0.82 | HTR1A (0.51) | CCR1GFERKMT2AMEN1LMNA | |
| SCHEMBL11294977 | 0.82 | CCR1 (0.46) | CCR1GFERKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061299-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |