Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | MMP1 | P03956 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MMP12 | P39900 | 2/20 | 0.55 |
| ▸ | UQCRB | P14927 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 8/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065124 | 0.91 | ALDH1A1 (0.53) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL30724544 | 0.86 | CA1 (0.58) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL1109 | 0.86 | CA1 (0.58) | CA1CA2CA12CA9MMP1 | |
| Water SCHEMBL1434222 | 0.84 | CA1 (0.56) | CA1CA2CA12CA9MMP1 | |
| Hydrochloric Acid SCHEMBL4638988 | 0.84 | CA1 (0.56) | CA1CA2CA12CA9MMP1 | |
| Hydrazine SCHEMBL28166174 | 0.84 | CA1 (0.56) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL29171227 | 0.84 | CA1 (0.56) | CA1CA2CA12CA9MMP1 | |
| Potassium SCHEMBL30724545 | 0.84 | CA1 (0.56) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL29171225 | 0.84 | CA1 (0.56) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL28202553 | 0.84 | CA1 (0.56) | CA1CA2CA12CA9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117535689-A | Method for synthesizing sulfonamide through decarbonylation of N, N-dimethylformamide and denitrification of sulfonyl hydrazide under electrochemical condition | 湘潭大学 | 2024-02-09 | — | — | CN | claimed |
| CN-116162046-A | Alkynyl sulfone derivative and preparation method and application thereof | 云南民族大学 | 2023-05-26 | — | — | CN | claimed |
| CN-113583309-A | Novel breathable waterproof rubber composite material and preparation method thereof | 青岛科技大学 | 2021-11-02 | — | — | CN | claimed |
| CN-113308032-A | Novel breathable waterproof rubber composite material and preparation method thereof | 青岛科技大学 | 2021-08-27 | — | — | CN | claimed |
| CN-116162046-B | Alkynyl sulfone derivative and preparation method and application thereof | 云南民族大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-117535689-A | Method for synthesizing sulfonamide through decarbonylation of N, N-dimethylformamide and denitrification of sulfonyl hydrazide under electrochemical condition | 湘潭大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-116162046-A | Alkynyl sulfone derivative and preparation method and application thereof | 云南民族大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-114016058-B | Method for electrochemically synthesizing alkyl sulfone compound | 桂林医学院 | 2022-12-16 | — | — | CN | disclosed |
| CN-112341376-B | Preparation method of cycloolefine amine sulfone derivative | 温州医科大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-114874630-A | High-rate platinum heat-vulcanized foamed silicone rubber and preparation method thereof | 浙江恒业成有机硅有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114016058-A | Method for electrochemically synthesizing alkyl sulfone compound | 桂林医学院 | 2022-02-08 | — | — | CN | disclosed |
| CN-113583309-A | Novel breathable waterproof rubber composite material and preparation method thereof | 青岛科技大学 | 2021-11-02 | — | — | CN | disclosed |
| US-20110118505-A1 | Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses | SIGA TECHNOLOGIES INC. (US) | 2011-05-19 | — | — | US | disclosed |
| US-20100256096-A1 | Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses | SIGA TECHNOLOGIES, INC. | 2010-10-07 | — | — | US | disclosed |
| CN-101641092-A | Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods of treating hemorrhagic fever viruses, including treatment of arenavirus-associated infections | SIGA TECHNOLOGIES INC US | 2010-02-03 | — | — | CN | disclosed |
| EP-2124921-A2 | SULFONYL SEMICARBAZIDES, CARBONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES | SIGA TECHNOLOGIES, INC. (US) | 2009-12-02 | — | — | EP | disclosed |
| US-20090203675-A1 | Sulfonyl Semicarbazides, Semicarbazides and Ureas, Pharmaceutical Compositions Thereof, and Methods for Treating Hemorrhagic Fever Viruses, Including Infections Associated with Arena Viruses | SIGA TECHNOLOGIES, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| WO-2008147474-A2 | SULFONYL SEMICARBAZIDES, CARBONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES | SIGA TECHNOLOGIES, INC. (US) | 2008-12-04 | — | — | WO | disclosed |
| EP-1827446-A2 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES | SIGA TECHNOLOGIES, INC. (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006062898-A2 | COMPOUNDS AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES | SIGA TECHNOLOGIES, INC. (US) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118505-A1 | Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses | SORD, GBA1, GK | CA1 4154/4885CA2 3268/4885CA12 3486/4885 |
| US-20100256096-A1 | Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses | GBA1, SORD, GK | CA1 4296/4885CA2 3236/4885CA12 3319/4885 |
| US-20090203675-A1 | Sulfonyl Semicarbazides, Semicarbazides and Ureas, Pharmaceutical Compositions Thereof, and Methods for Treating Hemorrhagic Fever Viruses, Including Infections Associated with Arena Viruses | GBA1, GK, GCK | CA1 3702/4885CA2 3360/4885CA12 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.