Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.78 |
| ▸ | HTT | P42858 | 2/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321662 | 0.83 | HSD17B10 (0.72) | KMT2AMEN1HTTHSD17B10GLA | |
| SCHEMBL3921265 | 0.82 | ALDH1A1 (0.60) | KMT2AMEN1HTTHSD17B10LMNA | |
| SCHEMBL944712 | 0.82 | HSD17B10 (0.70) | KMT2AMEN1HTTHSD17B10GLA | |
| SCHEMBL4328755 | 0.81 | HSD17B10 (1.00) | KMT2AMEN1HTTHSD17B10GLA | |
| SCHEMBL22663543 | 0.79 | HSD17B10 (0.58) | KMT2AMEN1HTTHSD17B10GLA | |
| SCHEMBL4337758 | 0.79 | HSD17B10 (0.74) | KMT2AMEN1HTTHSD17B10GLA | |
| SCHEMBL3627843 | 0.77 | HSD17B10 (0.66) | KMT2AMEN1HTTHSD17B10GLA | |
| SCHEMBL13873953 | 0.76 | HSD17B10 (1.00) | KMT2AMEN1HTTHSD17B10GLA | |
| SCHEMBL7492042 | 0.75 | POLB (0.66) | KMT2AMEN1HTTLMNAMAPT | |
| SCHEMBL7492048 | 0.75 | POLB (0.66) | KMT2AMEN1HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163697-A1 | Multicomponent coupling and glycopeptide synthesis with cyclic thioanhydrides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-06-25 | — | — | US | disclosed |
| US-20090163697-A1 | Multicomponent coupling and glycopeptide synthesis with cyclic thioanhydrides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163697-A1 | Multicomponent coupling and glycopeptide synthesis with cyclic thioanhydrides | LNPEP, CLSPN, GALNT14 | KMT2A 4163/4885MEN1 2100/4885HTT 788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.