Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923346 | 0.87 | MAPT (0.53) | ALDH1A1LMNAMAOBMEN1KMT2A | |
| SCHEMBL3915221 | 0.86 | HTT (0.72) | ALDH1A1LMNAMAOBMEN1KMT2A | |
| SCHEMBL3922167 | 0.84 | MEN1 (0.47) | ALDH1A1LMNAMAOBMEN1KMT2A | |
| SCHEMBL3923245 | 0.83 | HTT (0.52) | ALDH1A1LMNAMAOBMEN1KMT2A | |
| SCHEMBL4175139 | 0.82 | KMT2A (0.78) | ALDH1A1LMNAMEN1KMT2AHTT | |
| SCHEMBL3913448 | 0.81 | MAPT (0.58) | ALDH1A1LMNAMAOBMEN1KMT2A | |
| SCHEMBL7492042 | 0.77 | POLB (0.66) | ALDH1A1LMNAMEN1KMT2AHTT | |
| SCHEMBL7492048 | 0.77 | POLB (0.66) | ALDH1A1LMNAMEN1KMT2AHTT | |
| SCHEMBL1520824 | 0.75 | MAOB (1.00) | ALDH1A1LMNAMAOBMEN1KMT2A | |
| SCHEMBL3917727 | 0.72 | MAPT (0.62) | ALDH1A1MAOBMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270720-A1 | Iminothiazolidinone derivatives as SFRP-1 antagonists | WYETH (US) | 2006-11-30 | — | — | US | claimed |
| US-7563813-B2 | Iminothiazolidinone derivatives as SFRP-1 antagonists | WYETH (US) | 2009-07-21 | — | — | US | disclosed |
| US-20060270720-A1 | Iminothiazolidinone derivatives as SFRP-1 antagonists | WYETH (US) | 2006-11-30 | — | — | US | disclosed |
| WO-2006124887-A1 | IMINOTHIAZOLIDINONE DERIVATIVES AS SFRP-1 ANTAGONISTS | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270720-A1 | Iminothiazolidinone derivatives as SFRP-1 antagonists | SFRP1, FZD7, DKK1 | ALDH1A1 683/4885LMNA 4353/4885MAOB 4606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.