Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4175248 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HSD11B1GPR27PGR | |
| SCHEMBL4879959 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1LMNAHSD11B1GPR27 | |
| SCHEMBL23559201 | 0.80 | CHEK2 (0.61) | KDM4ECHEK2LMNAPGRSIRT2 | |
| SCHEMBL3462013 | 0.77 | GPR27 (0.60) | KDM4EALDH1A1LMNAGPR27PGR | |
| SCHEMBL4639661 | 0.77 | HSD11B1 (0.50) | ALDH1A1HSD11B1KMT2A | |
| SCHEMBL15480605 | 0.74 | KDM4E (0.63) | KDM4EALDH1A1LMNAHSD11B1SIRT2 | |
| SCHEMBL15480608 | 0.73 | NPSR1 (0.47) | LMNASIRT2MCOLN3MEN1KMT2A | |
| SCHEMBL14018589 | 0.73 | SMN1; SMN2 (0.48) | KDM4EALDH1A1LMNAHSD11B1GPR27 | |
| SCHEMBL714681 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1LMNAHSD11B1L3MBTL1 | |
| SCHEMBL1883655 | 0.71 | MAPT (0.60) | KDM4EALDH1A1GPR27MCOLN3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | disclosed |
| EP-1924554-A1 | SULPHONAMIDE DERIVATIVES | Biotie Therapies Corp. (FI) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007034035-A1 | SULPHONAMIDE DERIVATIVES | BIOTIE THERAPIES CORPORATION (FI) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | HCAR1, ADGRE5, ALK | KDM4E 854/4885CHEK2 4086/4885ALDH1A1 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.