Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MME | P08473 | 3/20 | 0.47 |
| ▸ | ECE1 | P42892 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185169 | 0.90 | NPC1 (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4NPC1 | |
| SCHEMBL4181935 | 0.87 | PLAAT3 (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4NPC1 | |
| SCHEMBL4174117 | 0.85 | ECE1 (0.48) | PLAAT3PLAAT5PLAAT2PLAAT4NPC1 | |
| SCHEMBL4175301 | 0.83 | FFAR1 (0.51) | PLAAT3PLAAT5PLAAT2PLAAT4NPC1 | |
| SCHEMBL4166987 | 0.82 | PLAAT3 (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4NPC1 | |
| SCHEMBL4186377 | 0.81 | PLAAT3 (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4NPC1 | |
| SCHEMBL4164307 | 0.81 | NPC1 (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4NPC1 | |
| SCHEMBL4173470 | 0.80 | FFAR1 (0.48) | PLAAT3PLAAT5PLAAT2PLAAT4NPC1 | |
| SCHEMBL4188513 | 0.79 | FFAR1 (0.54) | PLAAT3PLAAT5PLAAT2PLAAT4NPC1 | |
| SCHEMBL4186329 | 0.79 | ALDH1A1 (0.53) | PLAAT3PLAAT5PLAAT2PLAAT4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090182020-A1 | SUBSTITUTED BIS(HETERO)AROMATIC N--ETHYLPROPIOLAMIDES AND USE THEREOF FOR PRODUCTION OF MEDICAMENTS | GRUNENTHAL GMBH (DE) | 2009-07-16 | — | — | US | claimed |
| EP-1968935-A1 | SUBSTITUTED BIS(HETERO)AROMATIC N-ETHYLPROPIOLAMIDES AND USE THEREOF FOR PRODUCTION OF MEDICAMENTS | Grünenthal GmbH (DE) | 2008-09-17 | — | — | EP | claimed |
| WO-2007079958-A1 | SUBSTITUTED BIS(HETERO)AROMATIC N-ETHYLPROPIOLAMIDES AND USE THEREOF FOR PRODUCTION OF MEDICAMENTS | Grünenthal GmbH (DE) | 2007-07-19 | — | — | WO | claimed |
| US-20090182020-A1 | SUBSTITUTED BIS(HETERO)AROMATIC N--ETHYLPROPIOLAMIDES AND USE THEREOF FOR PRODUCTION OF MEDICAMENTS | GRUNENTHAL GMBH (DE) | 2009-07-16 | — | — | US | disclosed |
| EP-1968935-A1 | SUBSTITUTED BIS(HETERO)AROMATIC N-ETHYLPROPIOLAMIDES AND USE THEREOF FOR PRODUCTION OF MEDICAMENTS | Grünenthal GmbH (DE) | 2008-09-17 | — | — | EP | disclosed |
| EP-1264930-B1 | Cellulose fibers comprising radiation activatable resins | PROCTER & GAMBLE (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007079958-A1 | SUBSTITUTED BIS(HETERO)AROMATIC N-ETHYLPROPIOLAMIDES AND USE THEREOF FOR PRODUCTION OF MEDICAMENTS | Grünenthal GmbH (DE) | 2007-07-19 | — | — | WO | disclosed |
| US-6887347-B2 | Cellulose fibers comprising radiation activatable resin formalities | THE PROCTER AND GAMBLE COMPANY (US) | 2005-05-03 | — | — | US | disclosed |
| US-20040140070-A1 | Cellulose fibers comprising radiation activatable resin formalities | THE PROCTER & GAMBLE COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2002101139-A1 | CELLULOSE FIBERS COMPRISING RADIATION ACTIVATABLE RESINS | THE PROCTER & GAMBLE COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |
| EP-1264930-A1 | Cellulose fibers comprising radiation activatable resins | THE PROCTER & GAMBLE COMPANY (US) | 2002-12-11 | — | — | EP | disclosed |
| US-6090236-A | POLYMERIC WEB COATED WITH IRRADIATION-CURED RESIN PHOTOINITIATED WITH PHOTOINITIATOR HAVING A COVALENTLY BOUND SENSITIZING MOIETY SPECIFIC TO WAVELENGTH OF CURING RADIATION | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-5747550-A | Method of generating a reactive species and polymerizing an unsaturated polymerizable material | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-05-05 | — | — | US | disclosed |
| US-5739175-A | Photoreactor composition containing an arylketoalkene wavelength-specific sensitizer | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-04-14 | — | — | US | disclosed |
| US-5709955-A | LAMINATION, PHOTOREACTOR WITH WAVELENGTH-SPECIFIC SENSITIZER BONDED TO PHOTOINITIATOR | KIMBERLY-CLARK CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| US-5685754-A | FIBERS, WEBS, PHOTOSENSITIZER AND PHOTOINITIATOR COVALENTLY BONDED AS A PHOTOREACTOR | KIMBERLY-CLARK CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| US-5686503-A | PHOTOINITIATORS | KIMBERLY-CLARK CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182020-A1 | SUBSTITUTED BIS(HETERO)AROMATIC N--ETHYLPROPIOLAMIDES AND USE THEREOF FOR PRODUCTION OF MEDICAMENTS | FHIT, CYP3A43, DNPEP | PLAAT3 2664/4885PLAAT5 2707/4885PLAAT2 2933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.