⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385568 | 0.76 | CYP3A4 (0.40) | — | |
| SCHEMBL17193188 | 0.73 | TSHR (0.42) | — | |
| SCHEMBL1376187 | 0.70 | TSHR (0.36) | — | |
| SCHEMBL153124 | 0.67 | — | — | |
| SCHEMBL1589885 | 0.67 | PLAU (0.38) | — | |
| SCHEMBL1162948 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL1162577 | 0.67 | — | — | |
| SCHEMBL240193 | 0.65 | MAOA (0.34) | — | |
| SCHEMBL676633 | 0.65 | CYP1A2 (0.41) | — | |
| SCHEMBL2144679 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1327631-A2 | Fused heterocyclic compounds, their production and use as angiotensin II antagonists | Takeda Chemical Industries, Ltd. (JP) | 2003-07-16 | — | — | EP | claimed |
| EP-0518033-B1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-07-02 | — | — | EP | claimed |
| EP-0518033-A1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-16 | — | — | EP | claimed |
| US-11685711-B2 | Carbon monoxide-releasing molecules triggered by physiological stimuli | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20200283382-A1 | CARBON MONOXIDE-RELEASING MOLECULES TRIGGERED BY PHYSIOLOGICAL STIMULI | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-09-10 | — | — | US | disclosed |
| WO-2020067507-A1 | PRIMARY AMINE COMPOUND- OR SECONDARY AMINE COMPOUND-ACIDIC POLYSACCHARIDE CONJUGATE, AND METHOD FOR PRODUCING SAME | 生化学工業株式会社 | 2020-04-02 | — | — | WO | disclosed |
| WO-2019032879-A1 | CARBON MONOXIDE-RELEASING MOLECULES TRIGGERED BY PHYSIOLOGICAL STIMULI | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-02-14 | — | — | WO | disclosed |
| US-20090233962-A1 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1911751-A1 | AMIDE DERIVATIVE AND PESTICIDE CONTAINING SUCH COMPOUND | Mitsui Chemicals, Inc. (JP) | 2008-04-16 | — | — | EP | disclosed |
| EP-1327631-A2 | Fused heterocyclic compounds, their production and use as angiotensin II antagonists | Takeda Chemical Industries, Ltd. (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-0518033-B1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-5389641-A | Fused heterocyclic compounds, having angiotensin II antagonistic activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0518033-A1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |