Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP9 | P55211 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334119 | 0.77 | TRPA1 (0.42) | CYP1A2MAOAMAOBBCHE | |
| SCHEMBL16397452 | 0.77 | KDM4E (0.32) | CYP1A2 | |
| SCHEMBL3707901 | 0.72 | AHR (0.41) | CYP1A2MAOACYP2A6CES1MAOB | |
| SCHEMBL2514870 | 0.69 | METAP2 (0.31) | — | |
| SCHEMBL599812 | 0.68 | CYP1A2 (0.44) | CYP1A2MAOACYP2A6CES1MAOB | |
| SCHEMBL207848 | 0.68 | AHR (0.46) | CYP1A2MAOACYP2A6CES1MAOB | |
| SCHEMBL1750072 | 0.66 | MAOA (0.42) | CYP1A2MAOACYP2A6CES1MAOB | |
| SCHEMBL1750074 | 0.66 | MAOA (0.42) | CYP1A2MAOACYP2A6CES1MAOB | |
| SCHEMBL624689 | 0.65 | MEN1 (0.39) | MAOACES1MAOBBCHEAHR | |
| SCHEMBL4175339 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720517-A | AR inhibitor, composition thereof and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-03-19 | — | — | CN | claimed |
| WO-2023208165-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2023-11-02 | — | — | WO | claimed |
| US-7056354-B2 | Compounds derived from diaminopyrazole substituted by a heteroaromatic radical and their use in oxidation dyeing of keratinous fibers | L'OREAL (FR) | 2006-06-06 | — | — | US | claimed |
| US-20040255397-A1 | Compounds derived from diaminopyrazole substituted by a heteroaromatic radical and their use in oxidation dyeing of keratimous fibers | L'OREAL (FR) | 2004-12-23 | — | — | US | claimed |
| EP-1412348-A1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLE SUBSTITUTED BY A HETEROAROMATIC RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-04-28 | — | — | EP | claimed |
| WO-2003008405-A1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLE SUBSTITUTED BY A HETEROAROMATIC RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2003-01-30 | — | — | WO | claimed |
| US-20240231224-A9 | HALOGEN-AND ALIPHATIC-CONTAINING ORGANOTIN PHOTORESISTS AND METHODS THEREOF | LAM RESEARCH CORPORATION | 2024-07-11 | — | — | US | disclosed |
| WO-2024137876-A2 | SURFACE MODIFICATION OF METAL CATALYSTS WITH HYDROPHOBIC LIGANDS OR IONOMERS | TWELVE BENEFIT CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |
| US-20240200208-A1 | CO2 PURIFICATION AND REDUCTION SYSTEMS | SUMITOMO MITSUI BANKING CORPORATION | 2024-06-20 | — | — | US | disclosed |
| US-20240192590-A1 | APPARATUS AND PROCESS FOR EUV DRY RESIST SENSITIZATION BY GAS PHASE INFUSION OF A SENSITIZER | LAM RESEARCH CORPORATION | 2024-06-13 | — | — | US | disclosed |
| WO-2024123514-A1 | CO2 PURIFICATION AND REDUCTION SYSTEMS | TWELVE BENEFIT CORPORATION (US) | 2024-06-13 | — | — | WO | disclosed |
| CN-118159909-A | Gray tone resist and processing | 元平台技术有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2024108304-A1 | DITHIOL CHELATORS FOR METAL CONJUGATION TO ANTIBODIES | STANDARD BIOTOOLS CANADA INC. (CA) | 2024-05-30 | — | — | WO | disclosed |
| US-20050153877-A1 | Macrocyclic hepatitis C serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. | 2005-07-14 | — | — | US | disclosed |
| US-20040255397-A1 | Compounds derived from diaminopyrazole substituted by a heteroaromatic radical and their use in oxidation dyeing of keratimous fibers | L'OREAL (FR) | 2004-12-23 | — | — | US | disclosed |
| EP-1003751-A1 | HYDROXAMIC ACID SUBSTITUTED FUSED HETEROCYCLIC METALLOPROTEINASE INHIBITORS | AMGEN INC. (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-0948497-A2 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE | Amgen inc. (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1999025752-A1 | FUNCTIONALIZED RESIN FOR THE SYNTHESIS OF AMIDES AND PEPTIDES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-05-27 | — | — | WO | disclosed |
| WO-1999006410-A1 | HYDROXAMIC ACID SUBSTITUTED FUSED HETEROCYCLIC METALLOPROTEINASE INHIBITORS | AMGEN INC. (US) | 1999-02-11 | — | — | WO | disclosed |
| WO-1998024782-A2 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE | AMGEN INC. (US) | 1998-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153877-A1 | Macrocyclic hepatitis C serine protease inhibitors | PRSS1, SPINT2, TMPRSS4 | CYP1A2 378/4885MAOA 1985/4885CYP2A6 319/4885 |
| US-20040255397-A1 | Compounds derived from diaminopyrazole substituted by a heteroaromatic radical and their use in oxidation dyeing of keratimous fibers | KRT18, AOC1, XRCC5 | CYP1A2 250/4885MAOA 378/4885CYP2A6 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.