SCHEMBL2144679

SCHEMBL2144679

[C]1Cc2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9630603 1.00
SCHEMBL7548244 0.79 MAOA (0.37)
SCHEMBL7548249 0.79 MAOA (0.37)
SCHEMBL1162503 0.79 TSHR (0.31)
SCHEMBL4121654 0.74
SCHEMBL6594792 0.74
SCHEMBL1038154 0.74 MAPT (0.41)
SCHEMBL4396833 0.74 TSHR (0.46)
SCHEMBL141824 0.74 TSHR (0.46)
SCHEMBL8161643 0.73 MAOA (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130210887-A1 DENDRIMERS AS NON-VIRAL VEHICLES FOR GENE THERAPY UNIVERSIDAD DE CASTILLA LA MANCHA (ES) 2013-08-15 US claimed
EP-2543659-A1 DENDRIMERS AS NON-VIRAL VEHICLES FOR GENE THERAPY Universidad De Castilla La Mancha (ES) 2013-01-09 EP claimed
EP-2344452-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF Simon Fraser University (CA) 2011-07-20 EP claimed
WO-2010037207-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF SIMON FRASER UNIVERSITY (CA) 2010-04-08 WO claimed
US-20130210887-A1 DENDRIMERS AS NON-VIRAL VEHICLES FOR GENE THERAPY UNIVERSIDAD DE CASTILLA LA MANCHA (ES) 2013-08-15 US disclosed
EP-2543659-A1 DENDRIMERS AS NON-VIRAL VEHICLES FOR GENE THERAPY Universidad De Castilla La Mancha (ES) 2013-01-09 EP disclosed
EP-2344452-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF Simon Fraser University (CA) 2011-07-20 EP disclosed
WO-2010037207-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF SIMON FRASER UNIVERSITY (CA) 2010-04-08 WO disclosed
EP-0331312-B1 PROCESS FOR PREPARING ELASTOMERIC POLYARYLATE GRAFT COPOLYMERS AND POLYARYLATE BEARING ONE DIHYDROCYCLOBUTENE END GROUP AMOCO CORPORATION (US) 1992-11-11 EP disclosed
US-4937287-A Addition-condensation copolymers; oxidation and heat resistance, photostability AMOCO CORPORATION (US) 1990-06-26 US disclosed
US-4937297-A Photostability; solvent, stress, heat resistance; noncracking AMOCO CORPORATION (US) 1990-06-26 US disclosed
EP-0331312-A1 Process for preparing elastomeric polyarylate graft copolymers and polyarylate bearing one dihydrocyclobutene end group AMOCO CORPORATION (US) 1989-09-06 EP disclosed