Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CCR1 | P32246 | 2/20 | 0.54 |
| ▸ | CCR5 | P51681 | 2/20 | 0.54 |
| ▸ | CCR8 | P51685 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398699 | 0.79 | SLC40A1 (0.55) | KDM4ELMNAMAPTMMP2TSHR | |
| SCHEMBL194280 | 0.79 | KDM4E (0.54) | KDM4ELMNAMAPTMMP2TSHR | |
| SCHEMBL737516 | 0.79 | KDM4E (0.54) | KDM4ELMNAMAPTMMP2TSHR | |
| SCHEMBL1341511 | 0.79 | SLC40A1 (0.55) | KDM4ELMNAMAPTMMP2TSHR | |
| Hydrochloric Acid SCHEMBL27976997 | 0.78 | SLC40A1 (0.54) | KDM4ELMNAMAPTMMP2TSHR | |
| SCHEMBL6852617 | 0.76 | KDM4E (0.50) | KDM4ELMNAMAPTMMP2TSHR | |
| SCHEMBL11966088 | 0.76 | KDM4E (0.50) | KDM4ELMNAMAPTMMP2TSHR | |
| SCHEMBL736420 | 0.73 | MMP2 (0.44) | KDM4ELMNAMAPTMMP2TSHR | |
| SCHEMBL6852161 | 0.73 | KDM4E (0.47) | KDM4ELMNAMAPTMMP2TSHR | |
| SCHEMBL24693564 | 0.72 | KDM4E (0.45) | KDM4ELMNAMAPTMMP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955422-B | polycyclic compound | 三菱瓦斯化学株式会社 | 2023-08-22 | — | — | CN | claimed |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | MITSUBISHI GAS CHEMICAL CO (JP) | 2021-11-18 | — | — | US | claimed |
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2021-11-04 | — | — | US | claimed |
| CN-112955422-A | Polycyclic compounds | 三菱瓦斯化学株式会社 | 2021-06-11 | — | — | CN | claimed |
| WO-2020080558-A1 | POLYCYCLIC COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-04-23 | — | — | WO | claimed |
| WO-2020079225-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2020-04-23 | — | — | WO | claimed |
| CN-112955422-B | polycyclic compound | 三菱瓦斯化学株式会社 | 2023-08-22 | — | — | CN | disclosed |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | MITSUBISHI GAS CHEMICAL CO (JP) | 2021-11-18 | — | — | US | disclosed |
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2021-11-04 | — | — | US | disclosed |
| CN-112955422-A | Polycyclic compounds | 三菱瓦斯化学株式会社 | 2021-06-11 | — | — | CN | disclosed |
| WO-2020080558-A1 | POLYCYCLIC COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-04-23 | — | — | WO | disclosed |
| WO-2020079225-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2020-04-23 | — | — | WO | disclosed |
| CN-101111499-B | Substituted ethynyl gold-nitrogen-containing heterocyclic carbene complex and organic electroluminescent device using the same | UBE INDUSTRIES | 2012-05-23 | — | — | CN | disclosed |
| US-20090091243-A1 | Substituted Ethynyl Gold-Nitrogen Containing Heterocyclic Carbene Complex and Organic Electroluminescent Device Using the Same | UBE INDUSTRIES, LTD. (JP) | 2009-04-09 | — | — | US | disclosed |
| CN-101111499-A | Substituted ethynyl gold-nitrogenated heterocyclic carbene complex and organic electroluminescent device using same | UBE INDUSTRIES (JP) | 2008-01-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | CBR1, C1R, CBR3 | KDM4E 1132/4885LMNA 570/4885MAPT 4484/4885 |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | CBR1, CBR3, C1R | KDM4E 965/4885LMNA 721/4885MAPT 4486/4885 |
| US-20090091243-A1 | Substituted Ethynyl Gold-Nitrogen Containing Heterocyclic Carbene Complex and Organic Electroluminescent Device Using the Same | ACSL3, ATXN2L, ACSL1 | KDM4E 1868/4885LMNA 2067/4885MAPT 4507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.