Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959928 | 0.75 | — | — | |
| SCHEMBL4493382 | 0.75 | CCNA2 (0.44) | CCNA2CDK2CDK5CDK5R1CCNT1 | |
| SCHEMBL30644405 | 0.72 | LMNA (0.44) | CCNA2CDK2CDK5CDK5R1CCNT1 | |
| SCHEMBL3577722 | 0.71 | CCR1 (0.59) | CCNA2CDK2CDK5CDK5R1CCNT1 | |
| SCHEMBL5361682 | 0.71 | KDM4E (0.55) | CCNA2CDK2CDK5CDK5R1CCNT1 | |
| SCHEMBL18210579 | 0.71 | LMNA (0.46) | CCNA2CDK2CDK5CDK5R1CCNT1 | |
| SCHEMBL13851786 | 0.71 | LMNA (0.47) | CCNA2CDK2CDK5CDK5R1CCNT1 | |
| SCHEMBL30734434 | 0.70 | RXFP1 (0.33) | POLBMEN1KMT2AMAPTHTT | |
| SCHEMBL30734432 | 0.70 | RXFP1 (0.33) | POLBMEN1KMT2AMAPTHTT | |
| SCHEMBL15232070 | 0.70 | CCNA2 (0.46) | CCNA2CDK2CDK5CDK5R1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130225-A1 | MACROLIDES DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-05-21 | — | — | US | disclosed |
| US-20090130225-A1 | MACROLIDES DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-05-21 | — | — | US | disclosed |
| US-20090130225-A1 | MACROLIDES DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-05-21 | — | — | US | disclosed |
| EP-1960413-A2 | MACROLIDES DERIVATIVES AS ANTIBACTERIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007060618-A2 | MACROLIDES DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007060618-A2 | MACROLIDES DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130225-A1 | MACROLIDES DERIVATIVES AS ANTIBACTERIAL AGENTS | MGAM, MLX, MYCBP | CCNA2 2356/4885CDK2 1989/4885CDK5 2075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.