Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12265997 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL2943555 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL10694426 | 0.84 | SLC6A4 (0.52) | PPARGPPARASLC6A2CYP3A4CYP2C9 | |
| SCHEMBL7391806 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL5390078 | 0.84 | PPARG (0.57) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL10887450 | 0.81 | MMP8 (0.49) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL29223826 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2HIF1AALDH1A1CYP1A2MAPK1 | |
| SCHEMBL12266021 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2HIF1AALDH1A1CYP1A2MAPK1 | |
| SCHEMBL27908890 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1APPARGPPARASLC6A2 | |
| SCHEMBL6548605 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1APPARGPPARASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247609-B2 | Aminoacid derivatives containing a disulfanyl group in the form of mixed disulfanyl and aminopeptidase N inhibitors | Pharamleads (FR) | 2012-08-21 | — | — | US | disclosed |
| US-8247608-B2 | Aminoacid derivatives containing a disulfanyl group in the form of mixed disulfanyl and aminopeptidase N inhibitors | PHARMALEADS (FR) | 2012-08-21 | — | — | US | disclosed |
| US-20090131509-A1 | Aminoacid Derivatives Containing a Disulfanyl Group in the form of Mixed Disulfanyl and Aminopeptidase N Inhibitors | PHARMALEADS (FR) | 2009-05-21 | — | — | US | disclosed |
| US-20090012153-A1 | AMINOACID DERIVATIVES CONTAINING A DISULFANYL GROUP IN THE FORM OF MIXED DISULFANYL AND AMINOPEPTIDASE N INHIBITORS | PHARMALEADS (FR) | 2009-01-08 | — | — | US | disclosed |
| EP-0980239-A1 | COSMETIC SKIN CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998051274-A1 | COSMETIC SKIN CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 1998-11-19 | — | — | WO | disclosed |
| WO-1998051659-A1 | SALICYLOXY α-CARBOXY ACIDS AND PREPARATION THEREOF | UNILEVER PLC (GB) | 1998-11-19 | — | — | WO | disclosed |
| US-5762947-A | CONTROLLING OILY SKIN | ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-4670579-A | Telomerization of olefins | ETHYL CORPORATION (US) | 1987-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131509-A1 | Aminoacid Derivatives Containing a Disulfanyl Group in the form of Mixed Disulfanyl and Aminopeptidase N Inhibitors | HRH4, OPRL1, CNR2 | SMN1; SMN2 3606/4885HIF1A 657/4885PPARG 3496/4885 |
| US-20090012153-A1 | AMINOACID DERIVATIVES CONTAINING A DISULFANYL GROUP IN THE FORM OF MIXED DISULFANYL AND AMINOPEPTIDASE N INHIBITORS | HRH4, CNR2, OPRM1 | SMN1; SMN2 3486/4885HIF1A 739/4885PPARG 3376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.