Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16755643 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4ETSHRHSD17B10GAA | |
| SCHEMBL23035655 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4ETSHRHSD17B10GAA | |
| SCHEMBL27278135 | 0.80 | EPHX1 (0.55) | ALDH1A1KDM4ETSHRHSD17B10GAA | |
| SCHEMBL20943429 | 0.78 | ALDH1A1 (0.83) | ALDH1A1KDM4ETSHRHSD17B10GAA | |
| SCHEMBL11841388 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRHSD17B10GAA | |
| SCHEMBL27288004 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRHSD17B10GAA | |
| SCHEMBL4187065 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRHSD17B10GAA | |
| SCHEMBL1578840 | 0.74 | GAA (0.54) | ALDH1A1KDM4ETSHRHSD17B10GAA | |
| SCHEMBL67860 | 0.74 | ALDH1A1 (0.87) | ALDH1A1KDM4ETSHRHSD17B10GAA | |
| SCHEMBL27868338 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | HCAR1, ADGRE5, ALK | ALDH1A1 872/4885KDM4E 854/4885TSHR 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.