Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23035655 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAL3MBTL1LMNA | |
| SCHEMBL11841388 | 0.94 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAL3MBTL1LMNA | |
| SCHEMBL275597 | 0.82 | LMNA (0.79) | L3MBTL1LMNAMAPK1TSHRHPGD | |
| SCHEMBL4176097 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAAL3MBTL1MAPK1 | |
| SCHEMBL8812406 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4EGAAL3MBTL1MAPK1 | |
| SCHEMBL20943429 | 0.80 | ALDH1A1 (0.83) | ALDH1A1KDM4EGAAL3MBTL1LMNA | |
| SCHEMBL67860 | 0.80 | ALDH1A1 (0.87) | ALDH1A1KDM4EGAAL3MBTL1LMNA | |
| SCHEMBL472280 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAAL3MBTL1LMNA | |
| SCHEMBL14557293 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAL3MBTL1LMNA | |
| SCHEMBL11348649 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786290-A1 | PEPTIDES AND METHODS FOR THE CARBON-CARBON BOND FORMATION | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-03-03 | — | — | EP | disclosed |
| US-20150150893-A1 | ANDROGRAPHOLIDE ANALOGS AND THEIR USE FOR MEDICATION | LIAONING LIFENG SCIENT & TECHNOLOGY DEV COMPANY LTD (CN) | 2015-06-04 | — | — | US | disclosed |
| CN-102093385-B | Schiff base compounds as well as preparation method and application of Schiff base compounds | TIANJIN INST PHARM RESEARCH | 2013-03-27 | — | — | CN | disclosed |
| CN-102093385-A | Schiff base compounds as well as preparation method and application of Schiff base compounds | TIANJIN INST PHARM RESEARCH | 2011-06-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150150893-A1 | ANDROGRAPHOLIDE ANALOGS AND THEIR USE FOR MEDICATION | CYP11B1, CYP51A1, CYP11B2 | ALDH1A1 577/4885KDM4E 3717/4885GAA 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.