Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167988 | 0.84 | L3MBTL1 (0.49) | KEAP1NFE2L2OPRM1OPRL1L3MBTL1 | |
| SCHEMBL4181762 | 0.82 | MAOB (0.42) | L3MBTL1ALDH1A1RECQL | |
| SCHEMBL7518601 | 0.72 | NPSR1 (0.38) | KEAP1NFE2L2F2 | |
| SCHEMBL7517054 | 0.72 | F2 (0.41) | KEAP1NFE2L2F2ALDH1A1 | |
| SCHEMBL7522685 | 0.71 | F2 (0.40) | KEAP1NFE2L2F2 | |
| SCHEMBL7516866 | 0.71 | F2 (0.40) | KEAP1NFE2L2F2 | |
| SCHEMBL4743601 | 0.69 | F2 (0.38) | KEAP1NFE2L2F2ALDH1A1NR3C1 | |
| SCHEMBL14080753 | 0.68 | F2 (0.37) | KEAP1NFE2L2F2ALDH1A1NR3C1 | |
| SCHEMBL4746857 | 0.68 | SMN1; SMN2 (0.39) | KEAP1NFE2L2F2 | |
| SCHEMBL14080669 | 0.68 | F2 (0.37) | KEAP1NFE2L2F2ALDH1A1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143456-A1 | Polyamine Analogs as Modulators of Cell Migration and Cell Motility | PROGEN PHARMACEUTICALS, INC. | 2009-06-04 | — | — | US | disclosed |
| WO-2006086773-A2 | POLYAMINE ANALOGS AS MODULATORS OF CELL MIGRATION AND CELL MOTILITY | CELLGATE, INC. (US) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143456-A1 | Polyamine Analogs as Modulators of Cell Migration and Cell Motility | SRM, MIF, PTGIS | KEAP1 3851/4885NFE2L2 4434/4885OPRM1 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.