Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 3/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664008 | 0.82 | PTGDR (0.47) | PTGDRPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL3721674 | 0.78 | GBA1 (0.53) | ALDH1A1HSD17B10ALOX15MEN1LMNA | |
| SCHEMBL2242475 | 0.71 | PTGDR (0.54) | PTGDRPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL3724117 | 0.71 | MCL1 (0.40) | ALDH1A1SMN1; SMN2HSD17B10MAPTALOX15 | |
| SCHEMBL2240876 | 0.70 | PTGDR (0.55) | PTGDRPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL5022246 | 0.69 | ADORA2A (0.47) | PTGDRPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL5022980 | 0.68 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HSD17B10MAPTALOX15 | |
| SCHEMBL13895140 | 0.68 | PTGDR (0.60) | PTGDRPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL23291341 | 0.64 | ADORA2A (0.72) | ALDH1A1SMN1; SMN2HSD17B10MAPK1ADORA2A | |
| SCHEMBL9912208 | 0.64 | PTGDR (0.57) | PTGDRPIK3CAPIK3CBPIK3CGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242742-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2015-12-02 | — | — | EP | disclosed |
| US-8343966-B2 | Organic compounds | NOVARTIS AG (CH) | 2013-01-01 | — | — | US | disclosed |
| US-20090215776-A1 | Organic compounds | ADCOCK CLAIRE | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215776-A1 | Organic compounds | REN, RXFP1, MYLK | PTGDR 847/4885PIK3CA 3688/4885PIK3CB 4315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.