Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 3/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30297601 | 1.00 | MEN1 (1.00) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL17597245 | 0.89 | MEN1 (0.79) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL25277620 | 0.86 | MEN1 (0.76) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL8187780 | 0.85 | MEN1 (0.73) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL30620465 | 0.85 | MEN1 (0.73) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL1224829 | 0.85 | MEN1 (0.73) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL29475284 | 0.84 | MEN1 (0.72) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL29992449 | 0.83 | MEN1 (0.71) | MEN1KMT2APOLBMAPK1MAOA | |
| SCHEMBL74720 | 0.83 | MEN1 (0.71) | MEN1KMT2APOLBMAPK1MAOA | |
| Ethoxycarbonyl Group SCHEMBL28929781 | 0.83 | KMT2A (0.69) | MEN1KMT2APOLBMAPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 892 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118360801-A | Anti-pilling wool fabric and preparation method thereof | 王文俊 | 2024-07-19 | — | — | CN | claimed |
| CN-117886642-A | Selenium-rich nutrient solution for tartary buckwheat production and application | 成都大学 | 2024-04-16 | — | — | CN | claimed |
| CN-117886736-A | 2-indolyl-3-imine indoline derivative, preparation method and application thereof | 苏州昊帆生物股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-115350189-B | Application of sinomenine derivative in preparation of medicines for treating colorectal cancer | 兰州大学 | 2023-05-30 | — | — | CN | claimed |
| CN-114394963-B | Isoxazoline compound, preparation method and application | 西北农林科技大学 | 2023-05-23 | — | — | CN | claimed |
| CN-115350189-A | Application of neocelandine derivative in preparation of medicine for treating colorectal cancer | 兰州大学 | 2022-11-18 | — | — | CN | claimed |
| CN-115232052-A | Tetraindolylmethane compound and preparation method and application thereof | 南京工业大学 | 2022-10-25 | — | — | CN | claimed |
| CN-112574093-B | Novel green method for preparing 3-diaryl methyl substituted indole compound | 湖南理工学院 | 2022-10-04 | — | — | CN | claimed |
| CN-114940979-A | Method for improving cation-pi interaction by genetic code expansion and application | 浙江大学 | 2022-08-26 | — | — | CN | claimed |
| CN-114478348-A | Preparation method of 6-methoxyindole | 南京焕然生物科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-109761875-A | A kind of new method constructing amido bond | 盐城工学院 | 2019-05-17 | — | — | CN | claimed |
| CN-109678784-A | Thioetherification Benzazole compounds and preparation method thereof | 天津师范大学 | 2019-04-26 | — | — | CN | claimed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | claimed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | claimed |
| US-9486892-B2 | Polishing composition | FUJIMI INCORPORATED (JP) | 2016-11-08 | — | — | US | claimed |
| EP-1294366-B1 | PHARMACEUTICAL COMPOUNDS FOR TREATING COPD | ASTRAZENECA AB (SE) | 2004-08-18 | — | — | EP | claimed |
| US-20040029871-A1 | Pharmaceutical compounds for treating copd | ASTRAZENECA AB (SE) | 2004-02-12 | — | — | US | claimed |
| CN-1427718-A | Pharmaceutical compounds for the treatment of COPD | ASTRAZENECA AB (SE) | 2003-07-02 | — | — | CN | claimed |
| EP-1294366-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATING COPD | AstraZeneca AB (SE) | 2003-03-26 | — | — | EP | claimed |
| WO-2001085146-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATING COPD | ASTRAZENECA AB (SE) | 2001-11-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029871-A1 | Pharmaceutical compounds for treating copd | MPO, SERPINB1, CAT | MEN1 4804/4885KMT2A 3013/4885POLB 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.