Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 5/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | FSHR | P23945 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177516 | 1.00 | MMP1 (0.48) | MMP1MMP3MMP9KCNH2KMT2A | |
| SCHEMBL4177507 | 1.00 | MMP1 (0.48) | MMP1MMP3MMP9KCNH2KMT2A | |
| SCHEMBL4177514 | 1.00 | MMP1 (0.48) | MMP1MMP3MMP9KCNH2KMT2A | |
| SCHEMBL4166673 | 0.84 | KLK7 (0.41) | MMP1MMP3MMP9KMT2AKLK7 | |
| SCHEMBL4166684 | 0.84 | KLK7 (0.41) | MMP1MMP3MMP9KMT2AKLK7 | |
| SCHEMBL4166677 | 0.84 | KLK7 (0.41) | MMP1MMP3MMP9KMT2AKLK7 | |
| SCHEMBL4166683 | 0.84 | KLK7 (0.41) | MMP1MMP3MMP9KMT2AKLK7 | |
| SCHEMBL4059366 | 0.81 | TP53 (0.42) | MMP1MMP3MMP9KMT2AKLK7 | |
| SCHEMBL4159136 | 0.81 | TP53 (0.42) | MMP1MMP3MMP9KMT2AKLK7 | |
| SCHEMBL4173465 | 0.81 | TP53 (0.42) | MMP1MMP3MMP9KMT2AKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552208-B2 | Analogs of tetramic acid | University of Tennesseee Research Foundation (US) | 2013-10-08 | — | — | US | claimed |
| US-8552208-B2 | Analogs of tetramic acid | University of Tennesseee Research Foundation (US) | 2013-10-08 | — | — | US | disclosed |
| US-20090069406-A1 | Analogs of tetramic acid | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069406-A1 | Analogs of tetramic acid | TFRC, SLC7A1, FTH1 | MMP1 2172/4885MMP3 3351/4885MMP9 2455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.