Sugi Predict

Sugi Predict / Compounds / SCHEMBL4177987

SCHEMBL4177987

SCHEMBL4177987

Cn1c(I)cc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.53
▸ TERT O14746 1/20 0.50
▸ DAO P14920 1/20 0.50
▸ MCL1 Q07820 1/20 0.50
▸ MAPT P10636 3/20 0.47
▸ ALDH1A1 P00352 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ HPGD P15428 1/20 0.47
▸ RECQL P46063 1/20 0.47
▸ CA12 O43570 2/20 0.47
▸ CA9 Q16790 2/20 0.47
▸ BRD4 O60885 1/20 0.47
▸ BRPF1 P55201 1/20 0.47
▸ KAT2B Q92831 1/20 0.47
▸ BRD9 Q9H8M2 1/20 0.47
▸ SLC9A1 P19634 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ HTR2A P28223 1/20 0.42
▸ HTR2C P28335 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31914845 1.00 KMT2A (0.53) KMT2ATERTDAOMCL1MAPT
SCHEMBL10103705 0.76 KMT2A (0.76) KMT2ATERTDAOMCL1MAPT
SCHEMBL21955107 0.75 DAO (0.62) KMT2ATERTDAOMCL1MAPT
SCHEMBL31039545 0.75 DAO (0.62) KMT2ATERTDAOMCL1MAPT
SCHEMBL154592 0.74 KMT2A (0.55) KMT2ATERTDAOMCL1MAPT
SCHEMBL29378766 0.74 KMT2A (0.55) KMT2ATERTDAOMCL1MAPT
SCHEMBL14575430 0.74 KMT2A (0.36) KMT2ATERTDAOMCL1MAPT
SCHEMBL17207662 0.73 KMT2A (0.53) KMT2ATERTDAOMCL1MAPT
SCHEMBL2435291 0.73 KMT2A (0.53) KMT2ATERTDAOMCL1MAPT
SCHEMBL15417040 0.73 KMT2A (0.53) KMT2ATERTDAOMCL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4406957-B1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME NOGRA PHARMA LTD (IE) 2026-04-08 — — EP disclosed
US-12577256-B2 Aryl receptor modulators and methods of making and using the same NOGRA PHARMA LIMITED (IE) 2026-03-17 — — US disclosed
US-20250066384-A1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME NOGRA PHARMA LIMITED (IE) 2025-02-27 — — US disclosed
EP-4406957-A2 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME Nogra Pharma Limited (IE) 2024-07-31 — — EP disclosed
US-12012418-B2 Aryl receptor modulators and methods of making and using the same NOGRA PHARMA LIMITED (IE) 2024-06-18 — — US disclosed
EP-3160964-B1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME NOGRA PHARMA LTD (IE) 2024-03-13 — — EP disclosed
CN-116947880-A Aryl receptor modulators and methods of making and using the same 诺格拉制药有限公司 2023-10-27 — — CN disclosed
CN-111978319-B Aryl receptor modulators and methods of making and using the same 诺格拉制药有限公司 2023-08-11 — — CN disclosed
US-20230234963-A1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME NOGRA PHARMA LIMITED (IE) 2023-07-27 — — US disclosed
US-20230234963-A1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME NOGRA PHARMA LIMITED (IE) 2023-07-27 — — US disclosed
CN-104387407-A 6-methyl-6H-benzo[4, 5]thiophene[2, 3-b]indole and derivatives thereof as well as synthesis method of 6-methyl-6H-benzo[4, 5]thiophene[2, 3-b]indole and derivatives thereof UNIV XIANGTAN 2015-03-04 — — CN disclosed
EP-2408770-B1 BROAD SPECTRUM BENZOTHIOPHENE-NITROTHIAZOLIDE AND OTHER ANTIMICROBIALS Univ Virginia Patent Found (US) 2014-11-05 — — EP disclosed
CN-102985422-A Pyrrolopyridine and pyrrolopyrimidine inhibitors of kinases ABBVIE INC 2013-03-20 — — CN disclosed
US-20090238768-A1 MULTIMERIC MAGNETIC RESONANCE CONTRAST AGENTS AXELSSON OSKAR 2009-09-24 — — US disclosed
EP-1960393-A1 MULTIMERIC MAGENTIC RESONANCE CONTRAST AGENTS GE Healthcare AS (NO) 2008-08-27 — — EP disclosed
WO-2007064227-A1 MULTIMERIC MAGENTIC RESONANCE CONTRAST AGENTS GE HEALTHCARE AS (NO) 2007-06-07 — — WO disclosed
CN-1143636-A Indoles as insecticides and acaricides AMERICAN CYANAMID CO (US) 1997-02-26 — — CN disclosed
US-5599832-A INDOLES SUBSTITUTED WITH GROUPS BOTH ELECTRON WITHDRAWING AND LIPOPHILIC; GROWING, HARVESTING AND STORAGE OF CROPS AMERICAN CYANAMID COMPANY (US) 1997-02-04 — — US disclosed
US-5502071-A PLANTS AMERICAN CYANAMID COMPANY (US) 1996-03-26 — — US disclosed
EP-0697172-A1 Indoles as insecticides and acaricides AMERICAN CYANAMID COMPANY (US) 1996-02-21 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577256-B2 Aryl receptor modulators and methods of making and using the same AHR, IL23R, ARNT KMT2A 1428/4885TERT 3299/4885DAO 1734/4885
US-20250066384-A1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME AHR, IFNAR1, IL23R KMT2A 2217/4885TERT 3834/4885DAO 1401/4885
US-20090238768-A1 MULTIMERIC MAGNETIC RESONANCE CONTRAST AGENTS MAG, MSR1, FABP7 KMT2A 4110/4885TERT 2638/4885DAO 4665/4885
US-12012418-B2 Aryl receptor modulators and methods of making and using the same AHR, IL23R, IL2RA KMT2A 1625/4885TERT 3697/4885DAO 1331/4885
US-20230234963-A1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME AHR, IL23R, IL2RA KMT2A 1625/4885TERT 3697/4885DAO 1331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.