Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30617324 | 1.00 | KMT2A (0.53) | KMT2ADAOMCL1MAPTALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27972945 | 0.80 | MTNR1A (0.42) | KMT2ADAOMCL1MAPTALDH1A1 | |
| SCHEMBL8065707 | 0.77 | KMT2A (0.53) | KMT2ADAOMCL1MAPTALDH1A1 | |
| SCHEMBL10103705 | 0.76 | KMT2A (0.76) | KMT2ADAOMCL1MAPTALDH1A1 | |
| SCHEMBL21812440 | 0.76 | MCL1 (0.58) | KMT2AMCL1MAPTALDH1A1KDM4E | |
| SCHEMBL29891722 | 0.75 | DAO (0.62) | KMT2ADAOMCL1MAPTALDH1A1 | |
| SCHEMBL1421868 | 0.75 | DAO (0.62) | KMT2ADAOMCL1MAPTALDH1A1 | |
| SCHEMBL3197304 | 0.74 | NOTUM (0.38) | KMT2ADAOMCL1MAPTALDH1A1 | |
| SCHEMBL154592 | 0.74 | KMT2A (0.55) | KMT2ADAOMCL1MAPTALDH1A1 | |
| SCHEMBL29378766 | 0.74 | KMT2A (0.55) | KMT2ADAOMCL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106967213-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2019-11-05 | — | — | CN | claimed |
| CN-102459166-B | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2015-03-25 | — | — | CN | claimed |
| CN-110483524-A | The preparation method of indolocarbazole class compound | UNIV ZHEJIANG | 2019-11-22 | — | — | CN | disclosed |
| CN-106967213-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-106928120-B | Method for continuously preparing dicarbonyl indole compounds by using microchannel reaction device | 南京工业大学 | 2019-08-30 | — | — | CN | disclosed |
| CN-110114351-A | The heterocycle inhibitor of MCT4 | 维托尔股份有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-106661000-B | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2019-04-09 | — | — | CN | disclosed |
| CN-105408321-B | Indoles and azole derivatives, their preparation method and the pharmaceutical composition containing them | 法国施维雅药厂 | 2019-03-08 | — | — | CN | disclosed |
| CN-106715440-B | Imidazo isoindoles derivative, preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-109153643-A | Substituted indole MCL-1 inhibitors | 范德比尔特大学 | 2019-01-04 | — | — | CN | disclosed |
| CN-108349962-A | Substituted pyrazole and pyrrole compounds and methods of using the same for inhibiting translation initiation and treating diseases and disorders associated therewith | 班塔姆制药有限责任公司 | 2018-07-31 | — | — | CN | disclosed |
| US-8633182-B2 | Indanyloxyphenylcyclopropanecarboxylic acids | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| CN-102503881-B | Optically active tryptamine derivative and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2013-08-07 | — | — | CN | disclosed |
| CN-103180312-A | Heterocyclic compounds for treating or preventing disorders caused by reduced neurotransmission of serotonin, norephnephrine or dopamine | OTSUKA PHARMA CO LTD | 2013-06-26 | — | — | CN | disclosed |
| CN-103168039-A | Imidazopyridine type SYK inhibitors | GILEAD SCIENCES INC | 2013-06-19 | — | — | CN | disclosed |
| CN-103087078-A | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LAB | 2013-05-08 | — | — | CN | disclosed |
| CN-101077972-B | Organic light-emitting compound and organic electroluminescent device using the same | SAMSUNG DISPLAY CO LTD | 2012-12-26 | — | — | CN | disclosed |
| CN-102617443-A | Optically active indole derivative, synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2012-08-01 | — | — | CN | disclosed |
| CN-102503881-A | Optically active tryptamine derivative and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2012-06-20 | — | — | CN | disclosed |
| CN-101077972-A | Organic light-emitting compound and organic electroluminescent device using the same | SAMSUNG SDI CO LTD (KR) | 2007-11-28 | — | — | CN | disclosed |