SCHEMBL4178229

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4178238	1.00	TDP1 (0.50)	TDP1L3MBTL1NR1H3ALDH1A1ALDH2
	SCHEMBL4170167	0.90	L3MBTL1 (0.47)	TDP1L3MBTL1NR1H3KMT2AMEN1
	SCHEMBL4170170	0.90	L3MBTL1 (0.47)	TDP1L3MBTL1NR1H3KMT2AMEN1
	SCHEMBL4179881	0.85	NR1H3 (0.46)	TDP1L3MBTL1NR1H3ALDH1A1KMT2A
	SCHEMBL4176377	0.85	NR1H3 (0.46)	TDP1L3MBTL1NR1H3ALDH1A1KMT2A
	SCHEMBL4179885	0.85	NR1H3 (0.46)	TDP1L3MBTL1NR1H3ALDH1A1KMT2A
	SCHEMBL4176372	0.85	NR1H3 (0.46)	TDP1L3MBTL1NR1H3ALDH1A1KMT2A
	SCHEMBL4171946	0.85	ACHE (0.56)	TDP1L3MBTL1KMT2AMEN1LMNA
	SCHEMBL4170153	0.85	ACHE (0.56)	TDP1L3MBTL1KMT2AMEN1LMNA
	SCHEMBL4170157	0.85	ACHE (0.56)	TDP1L3MBTL1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.