Methylene Chloride

Methylene Chloride

SCHEMBL41783

CCOC(=O)CCO.ClCCl

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.56
MGAM O43451 1/20 0.56
SI P14410 1/20 0.56
MGAM2 Q2M2H8 1/20 0.56
CYP4F2 P78329 3/20 0.50
CYP4A11 Q02928 3/20 0.50
CYP1A2 P05177 1/20 0.50
ALDH1A1 P00352 5/20 0.46
TRPA1 O75762 1/20 0.46
LMNA P02545 2/20 0.40
HSD17B10 Q99714 2/20 0.40
NR1I2 O75469 1/20 0.40
PGR P06401 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
PTGS2 P35354 1/20 0.40
PDE4D Q08499 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
POLB P06746 2/20 0.39
TSHR P16473 2/20 0.39
ALOX15 P16050 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroform SCHEMBL11511595 0.94 GAA (0.50) GAAMGAMSIMGAM2CYP4F2
SCHEMBL30800905 0.93 GAA (0.65) GAAMGAMSIMGAM2CYP4F2
SCHEMBL6403 0.93
Ethyl Acetate SCHEMBL2500756 0.92 ALDH1A1 (0.56) GAAMGAMSIMGAM2CYP4F2
Hexane SCHEMBL16566680 0.92 DGKA (0.48) GAAMGAMSIMGAM2CYP4F2
SCHEMBL16698948 0.90
Water SCHEMBL2542900 0.90 GAA (0.62) GAAMGAMSIMGAM2CYP4F2
Hydrochloric Acid SCHEMBL2655390 0.90
Alcohol SCHEMBL9306984 0.90 GAA (0.62) GAAMGAMSIMGAM2CYP4F2
Water SCHEMBL555135 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 926 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986310-A Novel compound, namely rubusoside B, and preparation method and application thereof 湖南中医药大学 2024-05-07 CN claimed
CN-115650913-B Quinone quinoline compound and preparation method and application thereof 北京中医药大学 2024-03-01 CN claimed
CN-115350177-B Uric acid reducing function of extract and preparation method thereof 暨南大学 2023-06-06 CN claimed
CN-112538016-B Method for extracting chlorogenic acid n-butyl ester from peach blossom 黄河科技学院 2023-03-10 CN claimed
CN-113461747-B 2 compounds with hypoglycemic activity in rose hip 吉林化工学院 2023-02-03 CN claimed
CN-115650913-A Quinoid quinoline compound and preparation method and application thereof 北京中医药大学 2023-01-31 CN claimed
CN-115518096-A Integrated comprehensive extraction and separation method for effective components of epimedium 李玉山 2022-12-27 CN claimed
CN-115350177-A Uric acid reducing function of extract and preparation method thereof 暨南大学 2022-11-18 CN claimed
CN-115015418-A Quality detection method for Japanese ardisia herb decoction 湖南新汇制药股份有限公司 2022-09-06 CN claimed
CN-113773361-A Compound for treating hyperuricemia, composition thereof, preparation method and medical application 深圳弘汇生物医药有限公司 2021-12-10 CN claimed
CN-112538016-A Method for extracting chlorogenic acid n-butyl ester from peach blossom 黄河科技学院 2021-03-23 CN claimed
CN-111172202-A Phellinus strain of phellinus, and product, extract and application thereof 财团法人食品工业发展研究所 2020-05-19 CN claimed
CN-107556358-B Effective component of procoagulant cordyceps militaris and extraction and separation method and application thereof 黄河科技学院 2019-08-23 CN claimed
US-10099998-B2 Compound, and separation method, synthesis method and use thereof BEIJING PEKING UNIVERSITY WBL BIOTECH CO., LTD. (CN) 2018-10-16 US claimed
US-20180022688-A1 COMPOUND, AND SEPARATION METHOD, SYNTHESIS METHOD AND USE THEREOF BEIJING PEKING UNIVERSITY WBL BIOTECH CO., LTD. (CN) 2018-01-25 US claimed
CN-107207404-A Compound, its separation method, synthetic method and purposes 北京北大维信生物科技有限公司 2017-09-26 CN claimed
CN-105732613-B A kind of synthetic method of 9 demethyl (+) α dihydrotetrabenazineins 江苏省原子医学研究所 2017-08-15 CN claimed
CN-105732613-A Synthesis method of 9-demethyl-(+)-alpha-dihydrotetrabenazine 江苏省原子医学研究所 2016-07-06 CN claimed
CN-101057895-B 'Fuyanshu' preparation for treating gynopathy and its quality controlling method BEIJING QIYUAN YIDE INST OF MATERIA MEDICA 2010-05-19 CN claimed
CN-101057895-A 'Fuyanshu' preparation for treating gynopathy and its preparation method and quality controlling method and application QIYUANYIDE MEDICINES INST BEIJ (CN) 2007-10-24 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180022688-A1 COMPOUND, AND SEPARATION METHOD, SYNTHESIS METHOD AND USE THEREOF HMGCR, COASY, DHCR7 GAA 452/4885MGAM 629/4885SI 219/4885
US-10099998-B2 Compound, and separation method, synthesis method and use thereof HMGCR, COASY, DHCR7 GAA 452/4885MGAM 629/4885SI 219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.