SCHEMBL4178560

SCHEMBL4178560

CCCCCCNC(=O)COc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.67
RARG P13631 1/20 0.64
PLA2G4B P0C869 6/20 0.60
PLA2G4A P47712 1/20 0.60
TSHR P16473 2/20 0.60
RECQL P46063 1/20 0.60
TP53 P04637 1/20 0.59
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
ITGB3 P05106 1/20 0.55
ITGA2B P08514 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6539069 0.91 TSHR (0.67) RARBRARGPLA2G4BPLA2G4ATSHR
SCHEMBL4187728 0.86 KMT2A (0.55) RARBRARGTSHRRECQLNPC1
SCHEMBL14112030 0.84 RECQL (0.77) TSHRRECQLNPC1
SCHEMBL10599988 0.84 RECQL (0.77) TSHRRECQLNPC1
SCHEMBL7195953 0.82 TSHR (0.63) TSHRRECQLITGB3ITGA2B
SCHEMBL7195903 0.82 TSHR (0.63) TSHRRECQLITGB3ITGA2B
SCHEMBL8366672 0.82 RECQL (0.79) TSHRRECQLNPC1RAB9ASMN1; SMN2
SCHEMBL4511288 0.82 HTT (0.57) PLA2G4BTSHRRECQLNPC1RAB9A
SCHEMBL8943017 0.81 RARB (1.00) RARBPLA2G4BPLA2G4ATSHRTP53
SCHEMBL5858775 0.81 RARB (1.00) RARBPLA2G4BPLA2G4ATSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090176837-A1 COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS SONY CORPORATION (JP) 2009-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090176837-A1 COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS RARB, RARA, RARG RARB 1/4885RARG 3/4885PLA2G4B 507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.