Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.57 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.57 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573336 | 0.88 | KMT2A (0.57) | HTTSMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL6539069 | 0.88 | TSHR (0.67) | TSHRPLA2G4BITGB3ITGA2BRECQL | |
| SCHEMBL6539782 | 0.82 | SMN1; SMN2 (0.71) | HTTSMN1; SMN2USP2TSHRKMT2A | |
| SCHEMBL2835976 | 0.82 | ALDH1A1 (0.61) | KMT2AMEN1PLA2G4BPKMKDM4E | |
| SCHEMBL6539261 | 0.82 | PLA2G4B (0.60) | USP2TSHRKMT2AALOX15MAPK1 | |
| SCHEMBL4178560 | 0.82 | RARB (0.67) | SMN1; SMN2TSHRPLA2G4BITGB3ITGA2B | |
| SCHEMBL4509754 | 0.80 | ALDH1A1 (0.60) | HTTSMN1; SMN2USP2KMT2AMEN1 | |
| SCHEMBL22160248 | 0.79 | HTT (0.49) | HTTSMN1; SMN2TSHRKMT2AHSD17B10 | |
| SCHEMBL341847 | 0.79 | ALOX15 (0.65) | SMN1; SMN2KMT2AALOX15MEN1PLA2G4B | |
| SCHEMBL6538992 | 0.78 | GAA (0.61) | HTTSMN1; SMN2KMT2AMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120819-B2 | FGF-receptor agonist dimeric compounds | SANOFI (FR) | 2015-09-01 | — | — | US | disclosed |
| US-20090069368-A1 | FGF-RECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI-AVENTIS (FR) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069368-A1 | FGF-RECEPTOR AGONIST DIMERIC COMPOUNDS | FGF2, FGFR1, FGF1 | HTT 4673/4885SMN1; SMN2 3124/4885USP2 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.