SCHEMBL41789

SCHEMBL41789

NNc1nc2nc[nH]c2c(=O)[nH]1

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.63
PNP P00491 1/20 0.62
XDH P47989 3/20 0.58
POLA1 P09884 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22885 0.83 GDA (0.68) GDAPNPXDHPOLA1
SCHEMBL2051369 0.83 GDA (0.63) GDAPNPXDHPOLA1
SCHEMBL29407603 0.83 GDA (0.63) GDAPNPXDHPOLA1
SCHEMBL2983854 0.83 GDA (0.68) GDAPNPXDHPOLA1
SCHEMBL852109 0.83 GDA (0.63) GDAPNPXDHPOLA1
SCHEMBL1843779 0.83 GDA (0.63) GDAPNPXDHPOLA1
SCHEMBL20580 0.83 GDA (0.63) GDAPNPXDHPOLA1
SCHEMBL8886042 0.83 GDA (0.63) GDAPNPXDHPOLA1
Aspartic Acid SCHEMBL1519000 0.82 GDA (0.52) GDAPNPXDH
SCHEMBL5935074 0.81 XDH (0.78) GDAPNPXDHPOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111333649-B SNAP-tag technology-based cell membrane fluorescent probe and preparation and application thereof 中国科学院大连化学物理研究所 2022-06-03 CN claimed
CN-101784556-B Thiocarbon-protecting groups for rna synthesis AGILENT TECHNOLOGIES INC 2014-07-09 CN claimed
CN-103476947-A Enhanced biodistribution of oligomers GROOVE BIOPHARMA CORP 2013-12-25 CN claimed
CN-103068834-A Phosphoramidites for reverse RNA synthesis CHEMGENES CORP 2013-04-24 CN claimed
CN-102766182-A Method for synthesizing dideoxynucleoside through glycosyl transfer reaction and application thereof JIANGYIN SULI CHEMICAL CO LTD 2012-11-07 CN claimed
CN-1189562-C Antitumor antisense sequences directed against R1 and R2 components of ribonucleotide reductase GENESENSE TECHNOLOGIES INC (CA) 2005-02-16 CN claimed
CN-1160402-A Purine and guanine compounds as inhibitors of PNP CHIROSCIENCE LTD (GB) 1997-09-24 CN claimed
EP-4698674-A1 METHODS TO TREAT GLIOMA IN SUBJECTS WITH DEFINED TUMOUR MICROENVIRONMENT University Health Network (CA) 2026-02-25 EP disclosed
US-20260049318-A1 INHIBITION OF PLANT PROTEASE AED3-1 FOR IMPROVED HETEROLOGOUS PROTEIN PRODUCTION UNIV GUELPH (CA) 2026-02-19 US disclosed
EP-4638779-A1 STERILISED APPARATUS FOR CAPTURING NUCLEIC ACIDS FROM BODY FLUIDS Biocaptiva Limited (GB) 2025-10-29 EP disclosed
WO-2025217257-A1 ENGINEERED CIRCULARIZED PEGRNAS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2025-10-16 WO disclosed
EP-4615994-A1 DNAZYME FOR EOSINOPHIL PEROXIDASE AND USES THEREOF McMaster University (CA) 2025-09-17 EP disclosed
WO-2025085704-A1 BRAIN-CELL SPECIFIC PARTIAL CELLULAR REPROGRAMMING TREATMENT AND PREVENTION METHODS FOR ALZHEIMER'S DISEASE AND PROGERIA, COMPOSITIONS THEREFORE, AND USES THEREOF YOUTHBIO THERAPEUTICS INC. (US) 2025-04-24 WO disclosed
CN-1229084-A Unsaturated phosphate derivatives of purines and pyrimidines MERRELL DOW PHARMA (US) 1999-09-22 CN disclosed
CN-1212693-A Process for preparing purine derivatives HOFFMANN LA ROCHE (CH) 1999-03-31 CN disclosed
CN-1192154-A Combinatorial libraries of substrate-bound cyclic organic compounds CHIRON CORP (US) 1998-09-02 CN disclosed
CN-1120338-A Unsaturated phosphonate derivatives of purines and pyrimidines MERRELL DOW PHARMA (US) 1996-04-10 CN disclosed
US-5412088-A 6-O-substituted guanosine derivatives RUTGERS, THE STATE UNIVERSITY (US) 1995-05-02 US disclosed
CN-1036578-A NOVEL FLUOROPHOSPHONATE NUCLEOTIDE DERIVATIVES MERRELL DOW PHARMA (US) 1989-10-25 CN disclosed
EP-0310365-A1 Engine seal compatible dispersant for lubricating oils AMOCO CORPORATION (US) 1989-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049318-A1 INHIBITION OF PLANT PROTEASE AED3-1 FOR IMPROVED HETEROLOGOUS PROTEIN PRODUCTION DPP3, IDE, NOTCH3 GDA 495/4885PNP 1073/4885XDH 4554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.