Potassium

Potassium

SCHEMBL417892

COc1ccc(Oc2ccc(F)cc2)cc1CCCC(P(=O)(O)O)S(=O)(=O)O.[K].[K].[K]

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 9/20 0.70
PPARG P37231 5/20 0.40
PPARD Q03181 3/20 0.40
PPARA Q07869 3/20 0.40
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
TSPO P30536 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL417890 0.98 FDFT1 (0.70) FDFT1PPARGPPARDPPARAMTNR1A
Potassium SCHEMBL415177 0.87 FDFT1 (0.67) FDFT1
SCHEMBL10066426 0.86 FDFT1 (0.69) FDFT1
SCHEMBL415175 0.85 FDFT1 (0.67) FDFT1
Potassium Ion SCHEMBL417891 0.82 FDFT1 (1.00) FDFT1
Potassium SCHEMBL417848 0.80 FDFT1 (0.67) FDFT1
SCHEMBL1238247 0.78 FDFT1 (0.68) FDFT1
SCHEMBL417846 0.78 FDFT1 (0.67) FDFT1
SCHEMBL8619824 0.75 FDFT1 (0.47) FDFT1MTNR1BALDH1A1
SCHEMBL8619974 0.74 FDFT1 (0.56) FDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120022024-A1 ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-01-26 US disclosed
WO-2010123599-A9 ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2011-02-17 WO disclosed
WO-2010123599-A2 ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2010-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022024-A1 ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS CUTA, MMP8, CLPP FDFT1 1987/4885PPARG 4092/4885PPARD 4403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.