Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179150 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ATMGAATSHRHTR2A | |
| SCHEMBL4183323 | 0.94 | TSHR (0.44) | ALDH1A1ATMGAATSHRHTR2A | |
| SCHEMBL4171001 | 0.89 | ATM (0.41) | ALDH1A1ATMTSHRHTR2AHTR2C | |
| SCHEMBL4190119 | 0.88 | ATM (0.40) | ALDH1A1ATMGAATSHRHTR2A | |
| SCHEMBL4191772 | 0.88 | ATM (0.40) | ALDH1A1ATMGAATSHRHTR2A | |
| SCHEMBL4183317 | 0.87 | ATM (0.40) | ALDH1A1ATMTSHRHTR2AHTR2C | |
| SCHEMBL4185689 | 0.87 | ATM (0.42) | ALDH1A1ATMHTR2AHTR2CRAB9A | |
| SCHEMBL4185277 | 0.86 | ATM (0.41) | ALDH1A1ATMTSHRHTR2AHTR2C | |
| SCHEMBL4188234 | 0.85 | CTSL (0.44) | ATMGAATSHRRAB9ALMNA | |
| SCHEMBL4188233 | 0.85 | CTSL (0.44) | ATMGAATSHRRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124619-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2009-05-14 | — | — | US | claimed |
| US-20090124619-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124619-A1 | NOVEL COMPOUNDS | TRPV4, TRPC4, TRPV1 | ALDH1A1 961/4885ATM 4685/4885GAA 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.