Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 14/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 13/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 13/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | JUN | P05412 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771798 | 0.84 | MAPT (0.59) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL23598512 | 0.84 | MAPT (0.59) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL4183052 | 0.83 | USP2 (0.58) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL4189499 | 0.83 | CYP1A1 (0.62) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL4174253 | 0.78 | RAB9A (0.74) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL3659102 | 0.78 | RAB9A (0.74) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL17233312 | 0.78 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL23598790 | 0.77 | MAPT (0.48) | CYP1A2CYP1A1CYP1B1MAPTRAB9A | |
| SCHEMBL10275177 | 0.77 | CYP1A1 (0.62) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL10275586 | 0.76 | USP2 (0.60) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242742-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2015-12-02 | — | — | EP | disclosed |
| US-8343966-B2 | Organic compounds | NOVARTIS AG (CH) | 2013-01-01 | — | — | US | disclosed |
| US-20090215776-A1 | Organic compounds | ADCOCK CLAIRE | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215776-A1 | Organic compounds | REN, RXFP1, MYLK | CYP1A2 616/4885CYP1A1 339/4885CYP1B1 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.