Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173194 | 0.84 | MMP13 (0.78) | MMP13SLC22A8 | |
| SCHEMBL4258003 | 0.81 | MMP13 (1.00) | MMP13SLC22A8 | |
| SCHEMBL4180002 | 0.80 | MMP13 (0.70) | MMP13SLC22A8 | |
| SCHEMBL4180358 | 0.80 | MMP13 (0.72) | MMP13SLC22A8 | |
| SCHEMBL4177707 | 0.78 | MMP13 (0.68) | MMP13SLC22A8 | |
| SCHEMBL3648947 | 0.77 | MMP13 (1.00) | MMP13SLC22A8 | |
| SCHEMBL3805441 | 0.77 | MMP13 (1.00) | MMP13SLC22A8 | |
| SCHEMBL29673358 | 0.77 | MMP13 (1.00) | MMP13SLC22A8 | |
| SCHEMBL3803191 | 0.77 | MMP13 (1.00) | MMP13SLC22A8 | |
| SCHEMBL3803186 | 0.77 | MMP13 (1.00) | MMP13SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137637-A1 | Tetrazolyl-Methylene Amino Acid Derivatives | PFIZER INC. (US) | 2009-05-28 | — | — | US | claimed |
| EP-1828162-A1 | TETRAZOLYL-METHYLENE AMINO ACID DERIVATIVES | Warner-Lambert Company LLC (US) | 2007-09-05 | — | — | EP | claimed |
| WO-2006061706-A1 | TETRAZOLYL-METHYLENE AMINO ACID DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2006-06-15 | — | — | WO | claimed |
| US-20090137637-A1 | Tetrazolyl-Methylene Amino Acid Derivatives | PFIZER INC. (US) | 2009-05-28 | — | — | US | disclosed |
| EP-1828162-A1 | TETRAZOLYL-METHYLENE AMINO ACID DERIVATIVES | Warner-Lambert Company LLC (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006061706-A1 | TETRAZOLYL-METHYLENE AMINO ACID DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137637-A1 | Tetrazolyl-Methylene Amino Acid Derivatives | MMP13, MMP11, MMP3 | MMP13 1/4885SLC22A8 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.