SCHEMBL4180445

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4180439	1.00	NFE2L2 (0.44)	NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
	SCHEMBL4552109	1.00	NFE2L2 (0.44)	NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
	SCHEMBL4169581	0.89	NFE2L2 (0.42)	NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
	SCHEMBL4169585	0.89	NFE2L2 (0.42)	NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
	SCHEMBL4175534	0.89	GLA (0.42)	NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
	SCHEMBL4175539	0.89	GLA (0.42)	NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
	SCHEMBL4170999	0.88	NFE2L2 (0.43)	NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
	SCHEMBL4170993	0.88	NFE2L2 (0.43)	NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
	SCHEMBL8799920	0.88	NFE2L2 (0.58)	NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
	Ammonia Solution, Strong SCHEMBL27797122	0.85	NFE2L2 (0.46)	NFE2L2TRPA1CYP1A1CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.