Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4181282 | 1.00 | BDKRB1 (0.60) | BDKRB1 | |
| SCHEMBL3533254 | 0.84 | BDKRB1 (0.67) | BDKRB1 | |
| SCHEMBL3533258 | 0.84 | BDKRB1 (0.67) | BDKRB1 | |
| SCHEMBL5503691 | 0.83 | BDKRB1 (0.66) | BDKRB1 | |
| SCHEMBL4169800 | 0.83 | ALDH1A1 (0.44) | BDKRB1 | |
| SCHEMBL4169803 | 0.83 | ALDH1A1 (0.44) | BDKRB1 | |
| SCHEMBL3535119 | 0.83 | BDKRB1 (0.68) | BDKRB1 | |
| SCHEMBL4186841 | 0.80 | BDKRB1 (0.53) | BDKRB1 | |
| SCHEMBL4180773 | 0.80 | BDKRB1 (0.72) | BDKRB1 | |
| SCHEMBL4173208 | 0.80 | BDKRB1 (0.53) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227601-A1 | Bradykinin 1 Receptor Antagonists | AMGEN INC. (US) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227601-A1 | Bradykinin 1 Receptor Antagonists | BDKRB1, BDKRB2, VIPR1 | BDKRB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.