Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 18/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4169803 | 1.00 | ALDH1A1 (0.44) | ALDH1A1POLBMAPTBDKRB1 | |
| SCHEMBL4177146 | 0.84 | BDKRB1 (0.46) | ALDH1A1POLBMAPTBDKRB1 | |
| SCHEMBL4177150 | 0.84 | BDKRB1 (0.46) | ALDH1A1POLBMAPTBDKRB1 | |
| SCHEMBL4181279 | 0.83 | BDKRB1 (0.60) | BDKRB1 | |
| SCHEMBL4181282 | 0.83 | BDKRB1 (0.60) | BDKRB1 | |
| SCHEMBL4526154 | 0.75 | ALDH1A1 (0.77) | ALDH1A1POLBMAPTBDKRB1 | |
| SCHEMBL4526157 | 0.75 | ALDH1A1 (0.77) | ALDH1A1POLBMAPTBDKRB1 | |
| SCHEMBL3533258 | 0.65 | BDKRB1 (0.67) | BDKRB1 | |
| SCHEMBL3533254 | 0.65 | BDKRB1 (0.67) | BDKRB1 | |
| SCHEMBL3535119 | 0.65 | BDKRB1 (0.68) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227601-A1 | Bradykinin 1 Receptor Antagonists | AMGEN INC. (US) | 2009-09-10 | — | — | US | disclosed |
| EP-1963285-A1 | BRADYKININ 1 RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007067629-A1 | BRADYKININ 1 RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227601-A1 | Bradykinin 1 Receptor Antagonists | BDKRB1, BDKRB2, VIPR1 | ALDH1A1 2655/4885POLB 4406/4885MAPT 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.