Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188612 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1305896 | 0.94 | — | — | |
| SCHEMBL35675 | 0.81 | — | — | |
| SCHEMBL13254008 | 0.79 | — | — | |
| SCHEMBL24132076 | 0.77 | INMT (0.35) | — | |
| SCHEMBL14098007 | 0.77 | INMT (0.35) | — | |
| SCHEMBL3399972 | 0.77 | GAA (0.35) | — | |
| SCHEMBL10678677 | 0.74 | MAOA (0.34) | — | |
| SCHEMBL8429300 | 0.73 | ADRA2A (0.35) | — | |
| SCHEMBL24131989 | 0.72 | BRD4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507561-B1 | COMPOSITIONS FOR DELIVERING NUCLEIC ACIDS TO CELLS | MIRUS BIO CORP (US) | 2009-07-15 | — | — | EP | disclosed |
| US-20090124777-A1 | Compositions for Delivering Nucleic Acids to Cells | ROCHE MADISON INC. (US) | 2009-05-14 | — | — | US | disclosed |
| US-7498017-B2 | Compositions for delivering nucleic acids to cells | ROCHE MADISON INC. (US) | 2009-03-03 | — | — | US | disclosed |
| EP-1507561-A4 | COMPOSITIONS FOR DELIVERING NUCLEIC ACIDS TO CELLS | MIRUS BIO CORP (US) | 2007-08-01 | — | — | EP | disclosed |
| US-7220400-B2 | Compositions for delivering nucleic acids to cells | MIRUS BIO CORPORATION (US) | 2007-05-22 | — | — | US | disclosed |
| US-20060039860-A1 | Compositions for delivering nucleic acids to cells | ROCHE MADISON INC. | 2006-02-23 | — | — | US | disclosed |
| EP-1507561-A2 | COMPOSITIONS FOR DELIVERING NUCLEIC ACIDS TO CELLS | Mirus Corporation (US) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003099225-A2 | COMPOSITIONS FOR DELIVERING NUCLEIC ACIDS TO CELLS | MIRUS CORPORATION (US) | 2003-12-04 | — | — | WO | disclosed |
| US-20030220289-A1 | Compositions for delivering nucleic acids to cells | ROCHE MADISON INC. | 2003-11-27 | — | — | US | disclosed |
| EP-0087869-A1 | Process for the coproduction of carboxylic acids and acid anhydrides | BP Chemicals Limited (GB) | 1983-09-07 | — | — | EP | disclosed |