SCHEMBL4181942

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4186602	0.89	CBFB (0.82)	CBFBNPC1RAB9ASMN1; SMN2MAPK1
	SCHEMBL179151	0.86	CBFB (1.00)	CBFBNPC1RAB9ASMN1; SMN2KDM4E
	SCHEMBL4188605	0.85	CBFB (0.69)	CBFBDGAT1KCNH2NPBWR1METAP2
	SCHEMBL4177181	0.81	CBFB (0.59)	CBFBKIF20BDGAT1KCNH2KDM4E
	SCHEMBL4188875	0.79	CBFB (0.57)	CBFBCYP2C9
	SCHEMBL4173776	0.78	CBFB (0.64)	CBFBPARP1DGAT1KCNH2KDM4E
	SCHEMBL4188482	0.77	METAP2 (0.69)	CBFBNPC1RAB9AAURKAMETAP2
	SCHEMBL4174460	0.77	CBFB (0.62)	CBFBPARP1DHODHPARP2DGAT1
	SCHEMBL4179671	0.76	CBFB (0.56)	CBFBNPC1RAB9ASMN1; SMN2KDM4E
	SCHEMBL4174495	0.76	CBFB (0.61)	CBFBDGAT1KCNH2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.