Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | USP2 | O75604 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | MAOA | P21397 | 4/20 | 0.63 |
| ▸ | MAOB | P27338 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191801 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL4173475 | 0.86 | KDM4E (0.78) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL4175335 | 0.80 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL2349506 | 0.79 | KDM4E (0.83) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL29036860 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| 7-Hydroxy Isoflavone SCHEMBL5803559 | 0.79 | KDM4E (0.94) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| 7-Hydroxy Isoflavone SCHEMBL762528 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| Daidzein SCHEMBL19814 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| Daidzein SCHEMBL21114371 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| Daidzein SCHEMBL29374778 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | UNIVERSITY OF MISSISSIPPI | 2009-07-30 | — | — | US | disclosed |
| US-7468445-B2 | Antigiardial agents and use thereof | UNIVERSITY OF MISSISSIPPI (US) | 2008-12-23 | — | — | US | disclosed |
| US-20060106091-A1 | Antigiardial agents and use thereof | THE UNIVERSITY OF MISSISSIPPI | 2006-05-18 | — | — | US | disclosed |
| WO-2004014886-A1 | ANTIGIARDIAL AGENTS AND USE THEREOF | UNIVERSITY OF MISSISSIPPI (US) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106091-A1 | Antigiardial agents and use thereof | GPER1, ENPP2, ALPI | KDM4E 2433/4885ALDH1A1 2026/4885HSD17B10 1958/4885 |
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | ENPP2, GPER1, ALPI | KDM4E 2954/4885ALDH1A1 2472/4885HSD17B10 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.