Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.83 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.83 |
| ▸ | NPC1 | O15118 | 5/20 | 0.83 |
| ▸ | RAB9A | P51151 | 5/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.83 |
| ▸ | HPGD | P15428 | 4/20 | 0.83 |
| ▸ | MAPT | P10636 | 4/20 | 0.83 |
| ▸ | MAOA | P21397 | 4/20 | 0.83 |
| ▸ | MAOB | P27338 | 4/20 | 0.83 |
| ▸ | TP53 | P04637 | 3/20 | 0.83 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.83 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.83 |
| ▸ | CA12 | O43570 | 2/20 | 0.83 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892699 | 0.91 | ALDH2 (0.78) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| Daidzein SCHEMBL21114371 | 0.91 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| Daidzein SCHEMBL19814 | 0.91 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| Daidzein SCHEMBL29374778 | 0.91 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL13640741 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| Daidzein SCHEMBL19410270 | 0.87 | KDM4E (0.86) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL18235037 | 0.86 | KDM4E (0.74) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL2549643 | 0.85 | KDM4E (0.83) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL4683689 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL12289059 | 0.85 | KDM4E (0.83) | KDM4EALDH1A1HSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047420-B2 | MODULATION OF HAIR GROWTH | GILLETTE CO (US) | 2011-08-24 | — | — | EP | claimed |
| US-20240024490-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | THE BROAD INSTITUTE, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20230200388-A1 | COMPOUNDS AND METHODS FOR STIMULATING PLANTS | Sound Agriculture Company (US) | 2023-06-29 | — | — | US | disclosed |
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. | 2023-06-22 | — | — | US | disclosed |
| CN-109400568-B | 7-aryloxy acetoxyl isoflavone derivative and application thereof in pesticides | 江苏大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-107935928-B | Total diphenylpyrazole and preparation method and application thereof | 鲁东大学 | 2021-05-25 | — | — | CN | disclosed |
| US-20160317597-A1 | BEAN LEAVES OR BEAN STEMS HAVING HIGH ISOFLAVONE DERIVATIVES CONTENT AND METHOD FOR PREPARING SAME | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) | 2016-11-03 | — | — | US | disclosed |
| US-9408826-B2 | Isoflavone anti-viral compounds | Kineta, Inc. (US) | 2016-08-09 | — | — | US | disclosed |
| US-9408826-B2 | Isoflavone anti-viral compounds | Kineta, Inc. (US) | 2016-08-09 | — | — | US | disclosed |
| US-8680140-B2 | Phytoestrogenic formulations for alleviation or prevention of menopausal symptoms | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-03-25 | — | — | US | disclosed |
| US-20110262482-A1 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110262482-A1 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2011-10-27 | — | — | US | disclosed |
| US-7875735-B2 | such as haginin E, equol, daidzein, formononetin; dealkylation, hydroboration, oxidation in presence of base, oxidation-dehydrogenation using 2,3-dichloro-5,6-dicyanobenzoquinone, and deprotecting | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | disclosed |
| US-20100298581-A1 | Processes for Preparing Isoflavonoids using 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran as a Starting Material | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | disclosed |
| US-20100113586-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF MENOPAUSAL SYMPTOMS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2010-05-06 | — | — | US | disclosed |
| EP-1542675-A4 | COMPOUNDS USEFUL FOR THE INHIBITION OF ALDH | ENDOWMENT FOR RES IN HUMAN BIO (US) | 2008-11-19 | — | — | EP | disclosed |
| US-7368434-B2 | Compounds useful for the inhibition of ALDH | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 2008-05-06 | — | — | US | disclosed |
| EP-1542675-A1 | COMPOUNDS USEFUL FOR THE INHIBITION OF ALDH | The Endowment For Research In Human Biology, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20040068003-A1 | Compounds useful for the inhibition of ALDH | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC, | 2004-04-08 | — | — | US | disclosed |
| WO-2004002470-A1 | COMPOUNDS USEFUL FOR THE INHIBITION OF ALDH | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160317597-A1 | BEAN LEAVES OR BEAN STEMS HAVING HIGH ISOFLAVONE DERIVATIVES CONTENT AND METHOD FOR PREPARING SAME | ESR1, ECE2, ECE1 | KDM4E 1103/4885ALDH1A1 2732/4885HSD17B10 1442/4885 |
| US-20110262482-A1 | ANTI-VIRAL COMPOUNDS | MAVS, EIF2AK2, IRF3 | KDM4E 2601/4885ALDH1A1 3477/4885HSD17B10 4165/4885 |
| US-20100298581-A1 | Processes for Preparing Isoflavonoids using 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran as a Starting Material | EGLN2, HABP2, CYP8B1 | KDM4E 1268/4885ALDH1A1 3364/4885HSD17B10 275/4885 |
| US-20240024490-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | COASY, JMJD7, PTMS | KDM4E 2788/4885ALDH1A1 1238/4885HSD17B10 527/4885 |
| US-20100113586-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF MENOPAUSAL SYMPTOMS | ESR1, GPER1, SHBG | KDM4E 2421/4885ALDH1A1 3858/4885HSD17B10 2855/4885 |
| US-20230200388-A1 | COMPOUNDS AND METHODS FOR STIMULATING PLANTS | SNRK, GRK1, PPIP5K2 | KDM4E 4438/4885ALDH1A1 4111/4885HSD17B10 2779/4885 |
| US-20040068003-A1 | Compounds useful for the inhibition of ALDH | ALDH2, ALDH1A1, ALDH3A1 | KDM4E 1630/4885ALDH1A1 2/4885HSD17B10 41/4885 |
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | ERBB2, ACP1, TK1 | KDM4E 2301/4885ALDH1A1 2221/4885HSD17B10 3033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.