Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL4182370

C[S+](C)[O-].C[S+](C)[O-].O=C(O)C(F)(F)F

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MAP2K1MAP2K2

The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35
ACLY P53396 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
F2 P00734 1/20 0.33
F11 P03951 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
THRB P10828 1/20 0.32
CA2 P00918 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL4069871 1.00 ALDH1A1 (0.35) ALDH1A1TSHRACLYL3MBTL1F2
Trifluoroacetic Acid SCHEMBL27831673 0.97 ALDH1A1 (0.33) ALDH1A1TSHRACLYL3MBTL1F2
Dimethyl Sulfoxide SCHEMBL28260226 0.81 CA1 (0.33) CA2
Trifluoroacetic Acid SCHEMBL28747664 0.81 ALDH1A1 (0.37) ALDH1A1TSHRACLYL3MBTL1THRB
Trifluoroacetic Acid SCHEMBL3499424 0.79
Trifluoroacetic Acid SCHEMBL72727 0.79
Trifluoroacetic Acid SCHEMBL1262416 0.79
Trifluoroacetic Acid SCHEMBL4598430 0.79
Trifluoroacetic Acid SCHEMBL7814389 0.79 ALDH1A1 (0.44) ALDH1A1TSHRACLYL3MBTL1THRB
Trifluoroacetic Acid SCHEMBL2484766 0.79 ALDH1A1 (0.44) ALDH1A1TSHRACLYL3MBTL1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1864129-A4 DOXORUBICIN IMMUNOASSAY SALADAX BIOMEDICAL INC (US) 2009-02-18 EP disclosed
EP-1864129-A1 DOXORUBICIN IMMUNOASSAY Saladax Biomedical Inc. (US) 2007-12-12 EP disclosed
WO-2006104970-A1 DOXORUBICIN IMMUNOASSAY SALADAX BIOMEDICAL INC. (US) 2006-10-05 WO disclosed
EP-1689699-A2 ANTHRANILIC ACID DERIVATIVES AND THEIR USE AS ACTIVATORS OF THE HM74A RECEPTOR SMITHKLINE BEECHAM CORPORATION (US) 2006-08-16 EP disclosed
WO-2005016867-A2 ANTHRANILIC ACID DERIVATIVES AND THEIR USE AS ACTIVATORS OF THE HM74A RECEPTOR SMITHKLINE BEECHAM CORPORATION (US) 2005-02-24 WO disclosed
EP-1326593-A1 ESTROGEN RECEPTOR-$g(b) LIGANDS AstraZeneca AB (SE) 2003-07-16 EP disclosed
WO-2002030407-A1 ESTROGEN RECEPTOR-β LIGANDS ASTRAZENECA AB (SE) 2002-04-18 WO disclosed