Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011307 | 0.94 | MAOB (0.53) | BCHEMAOBCYP4F2CYP4A11MAOA | |
| SCHEMBL3922951 | 0.84 | CCNT1 (0.42) | — | |
| SCHEMBL80829 | 0.81 | MAOB (0.68) | BCHEMAOBCYP4F2CYP4A11MAOA | |
| SCHEMBL29411728 | 0.81 | MAOB (0.68) | BCHEMAOBCYP4F2CYP4A11MAOA | |
| SCHEMBL24646015 | 0.81 | CYP4F2 (0.55) | BCHEMAOBCYP4F2CYP4A11MAOA | |
| SCHEMBL30211112 | 0.81 | CYP4F2 (0.55) | BCHEMAOBCYP4F2CYP4A11MAOA | |
| SCHEMBL10867669 | 0.80 | CETP (0.52) | — | |
| SCHEMBL8011004 | 0.80 | ALOX5 (0.51) | BCHEMAOBNR4A2 | |
| SCHEMBL915329 | 0.78 | KDM4E (0.46) | CYP2D6 | |
| SCHEMBL2074050 | 0.78 | FFAR1 (0.45) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076508-A2 | BIARYL ETHER UREA COMPOUNDS | Pfizer Products Inc. (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008047229-A2 | BIARYL ETHER UREA COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-04-24 | — | — | WO | disclosed |