SCHEMBL418278

SCHEMBL418278

CN1CCC[C@H]1c1ccc(O)nc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
CHRNA7 P36544 2/20 0.56
CHRNB2 P17787 2/20 0.56
CHRNB4 P30926 2/20 0.56
CHRNA3 P32297 2/20 0.56
CHRNA4 P43681 2/20 0.56
CHRNA2 Q15822 2/20 0.56
LMNA P02545 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
HTR3E A5X5Y0 1/20 0.56
PSIP1 O75475 1/20 0.56
TRPA1 O75762 1/20 0.56
HTR3B O95264 1/20 0.56
CHRNA1 P02708 1/20 0.56
CHRNG P07510 1/20 0.56
MAPT P10636 1/20 0.56
CHRNB1 P11230 1/20 0.56
CYP2A6 P11509 1/20 0.56
PTGS1 P23219 1/20 0.56
CHRNA5 P30532 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL419658 1.00 ALDH1A1 (0.56) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL454514 1.00 ALDH1A1 (0.56) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL30363349 1.00 ALDH1A1 (0.56) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
Cyanide SCHEMBL27942324 0.95 ALDH1A1 (0.52) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL30618802 0.83 ALDH1A1 (0.64) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL29766108 0.83 ALDH1A1 (0.64) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL157172 0.82 CHRNA7 (0.62) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL30866542 0.82 CHRNA7 (0.62) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL5249340 0.82 CHRNA7 (0.62) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL29173751 0.82 CHRNA7 (0.62) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12110532-B2 In vitro glycosylation of proteins and enzymes DESIGN- ZYME LLC (US) 2024-10-08 US claimed
US-20240260865-A1 METHOD OF PRODUCING THIN ENZYME-BASED SENSING LAYERS ON PLANAR SENSORS CALIFORNIA INSTITUTE OF TECHNOLOGY 2024-08-08 US claimed
US-20240148248-A1 WIRELESS AUTOMATED ANIMAL MONITORING SYSTEM CALIFORNIA INSTITUTE OF TECHNOLOGY 2024-05-09 US claimed
US-11969246-B2 Method of producing thin enzyme-based sensing layers on planar sensors CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-04-30 US claimed
US-11903708-B2 Switchable low voltage electrochemical sensing for interfering species rejection CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-02-20 US claimed
US-20230363672-A1 METHOD OF PRODUCING THIN ENZYME-BASED SENSING LAYERS ON PLANAR SENSORS CALIFORNIA INSTITUTE OF TECHNOLOGY 2023-11-16 US claimed
US-11690544-B2 Method of producing thin enzyme-based sensing layers on planar sensors CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-07-04 US claimed
US-20230203557-A1 IN VITRO GLYCOSYLATION OF PROTEINS AND ENZYMES Design-Zyme LLC (US) 2023-06-29 US claimed
US-11666216-B2 Wireless automated animal monitoring system CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-06-06 US claimed
US-11643676-B2 In vitro glycosylation of proteins and enzymes Design-Zyme LLC (US) 2023-05-09 US claimed
EP-0658096-A4 STABILIZED CHEWABLE ANTIMICROBIAL ANIMAL FOODSTUFF. MONTGOMERY ROBERT E (US) 1995-04-24 EP claimed
EP-0614352-A4 ANTIMICROBIAL DENTIFRICE. MONTGOMERY ROBERT E (US) 1994-12-07 EP claimed
EP-0614352-A1 ANTIMICROBIAL DENTIFRICE MONTGOMERY, Robert E. (US) 1994-09-14 EP claimed
US-5310541-A Antimicrobial rawhide animal chew containing an oxidoreductase and oxidoreductase substrate ORACEUTICAL INNOVATIVE PROPERTIES LLC 1994-05-10 US claimed
WO-1994005252-A1 STABILIZED CHEWABLE ANTIMICROBIAL ANIMAL FOODSTUFF MONTGOMERY ROBERT E (US) 1994-03-17 WO claimed
WO-1994004127-A1 STABILIZED ENZYMATIC ANTIMICROBIAL COMPOSITIONS MONTGOMERY ROBERT E (US) 1994-03-03 WO claimed
US-5270033-A Antimicrobial composition and method of making same ORACEUTICAL INNOVATIVE PROPERTIES LLC 1993-12-14 US claimed
US-5262151-A Addition of catalase together with oxidoreductase prevents formation of hydrogen peroxide so prevent the salivary peroxidase system producing hypothiocyanite ORACEUTICAL INNOVATIVE PROPERTIES LLC 1993-11-16 US claimed
WO-1993010752-A1 ANTIMICROBIAL DENTIFRICE MONTGOMERY ROBERT E (US) 1993-06-10 WO claimed
US-5176899-A Containing an oxidoreductase enzyme ORACEUTICAL INNOVATIVE PROPERTIES LLC 1993-01-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203557-A1 IN VITRO GLYCOSYLATION OF PROTEINS AND ENZYMES ALDH7A1, OGA, DAO ALDH1A1 64/4885CHRNA7 2503/4885CHRNB2 3251/4885
US-12110532-B2 In vitro glycosylation of proteins and enzymes ALDH7A1, OGA, DAO ALDH1A1 64/4885CHRNA7 2503/4885CHRNB2 3251/4885
US-11643676-B2 In vitro glycosylation of proteins and enzymes ALDH7A1, OGA, DAO ALDH1A1 64/4885CHRNA7 2503/4885CHRNB2 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.