Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.62 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.62 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.62 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.62 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.62 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.62 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.62 |
| ▸ | HTR3B | O95264 | 1/20 | 0.62 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.62 |
| ▸ | CHRNG | P07510 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30866542 | 1.00 | CHRNA7 (0.62) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL29173751 | 1.00 | CHRNA7 (0.62) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL5249340 | 1.00 | CHRNA7 (0.62) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL29506366 | 0.97 | CHRNA7 (0.59) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| Acetic Acid SCHEMBL27199911 | 0.91 | KDM4E (0.55) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| Acetic Acid SCHEMBL31344183 | 0.91 | KDM4E (0.55) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| Glycerin SCHEMBL28748574 | 0.88 | ALDH1A1 (0.50) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| Glycolic Acid SCHEMBL31460410 | 0.88 | KDM4E (0.52) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| Succinic Acid SCHEMBL27606657 | 0.88 | KDM4E (0.52) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| Benzoic Acid SCHEMBL31344150 | 0.85 | KDM4E (0.53) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260107969-A1 | AEROSOL GENERATING MATERIAL COMPRISING A SUBSTITUTED 3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE COMPOUND | RAI STRATEGIC HOLDINGS INC (US) | 2026-04-23 | — | — | US | claimed |
| EP-4683527-A1 | VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF | Ready Mix Naturals, LLC (US) | 2026-01-28 | — | — | EP | claimed |
| US-20250289796-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | Ready Mix Naturals, LLC (US) | 2025-09-18 | — | — | US | claimed |
| US-20250241354-A1 | ORAL PRODUCTS | RAI STRATEGIC HOLDINGS INC (US) | 2025-07-31 | — | — | US | claimed |
| US-12358889-B2 | Vaporizable alkaloid compositions and methods of use thereof | Ready Mix Naturals, LLC (US) | 2025-07-15 | — | — | US | claimed |
| US-12358888-B2 | Vaporizable alkaloid compositions and methods of use thereof | Ready Mix Naturals, LLC (US) | 2025-07-15 | — | — | US | claimed |
| WO-2025118737-A1 | NICOTINE REPLACEMENT LIQUID PREPARATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 思摩尔国际控股有限公司 | 2025-06-12 | — | — | WO | claimed |
| WO-2025118385-A1 | NICOTINE LIQUID PREPARATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 思摩尔国际控股有限公司 | 2025-06-12 | — | — | WO | claimed |
| CN-120113830-A | Nicotine-substituted liquid preparation and preparation method and application thereof | 思摩尔国际控股有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120113831-A | Nicotine liquid preparation and preparation method and application thereof | 思摩尔国际控股有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-117164553-A | Synthesis method of 6-methyl nicotine and application of 6-methyl nicotine in tobacco tar | 深圳康润生物科技有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-114195759-B | Preparation method of 2-methyl-5- (1-methylpyrrolidine-2-yl) pyridine | 上海零诺生物科技有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-114437025-B | Racemization 6-methyl nicotine and preparation method and application thereof | 上海零诺生物科技有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-114437031-B | Synthesis method of 6-methyl nicotine | 深圳市真味生物科技有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-115611857-A | Preparation method of 2-methyl-5- (1-methylpyrrolidine-2-yl) pyridine | 上海伍夫科技有限公司 | 2023-01-17 | — | — | CN | claimed |
| CN-114989135-A | Organic acid salt of 2-methyl-5- (1-methylpyrrolidine-2-yl) pyridine and preparation method thereof | 广州天然科技有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-114437031-A | Synthetic method of 6-methyl nicotine | 深圳市真味生物科技有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-114437025-A | Racemic 6-methylnicotine and preparation method and application thereof | 上海零诺生物科技有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-114403494-A | Electronic cigarette oil without nicotine and preparation method thereof | 深圳市德森生物科技有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-114195759-A | Preparation method of 2-methyl-5- (1-methylpyrrolidine-2-yl) pyridine | 广州天然科技有限公司 | 2022-03-18 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260107969-A1 | AEROSOL GENERATING MATERIAL COMPRISING A SUBSTITUTED 3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE COMPOUND | CHRM1, CHRM3, ATRIP | CHRNA7 762/4885CHRNB2 800/4885CHRNA4 401/4885 |
| US-20250289796-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | OR10J3, TRPA1, TAS2R3 | CHRNA7 254/4885CHRNB2 389/4885CHRNA4 315/4885 |
| US-12358888-B2 | Vaporizable alkaloid compositions and methods of use thereof | SRM, SCLY, SMOX | CHRNA7 81/4885CHRNB2 98/4885CHRNA4 26/4885 |
| US-12358889-B2 | Vaporizable alkaloid compositions and methods of use thereof | SRM, SCLY, SMOX | CHRNA7 81/4885CHRNB2 98/4885CHRNA4 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.