SCHEMBL454514

SCHEMBL454514

CN1CCCC1c1ccc(O)nc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
CHRNA7 P36544 2/20 0.56
CHRNB2 P17787 2/20 0.56
CHRNB4 P30926 2/20 0.56
CHRNA3 P32297 2/20 0.56
CHRNA4 P43681 2/20 0.56
CHRNA2 Q15822 2/20 0.56
LMNA P02545 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
HTR3E A5X5Y0 1/20 0.56
PSIP1 O75475 1/20 0.56
TRPA1 O75762 1/20 0.56
HTR3B O95264 1/20 0.56
CHRNA1 P02708 1/20 0.56
CHRNG P07510 1/20 0.56
MAPT P10636 1/20 0.56
CHRNB1 P11230 1/20 0.56
CYP2A6 P11509 1/20 0.56
PTGS1 P23219 1/20 0.56
CHRNA5 P30532 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418278 1.00 ALDH1A1 (0.56) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL419658 1.00 ALDH1A1 (0.56) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL30363349 1.00 ALDH1A1 (0.56) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
Cyanide SCHEMBL27942324 0.95 ALDH1A1 (0.52) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL30618802 0.83 ALDH1A1 (0.64) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL29766108 0.83 ALDH1A1 (0.64) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL157172 0.82 CHRNA7 (0.62) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL30866542 0.82 CHRNA7 (0.62) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL5249340 0.82 CHRNA7 (0.62) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3
SCHEMBL29173751 0.82 CHRNA7 (0.62) ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025054345-A1 GENETIC ELEMENTS FOR ADJUSTMENT OF EXPRESSION Remedium Bio, Inc. (US) 2025-03-13 WO claimed
US-20240148248-A1 WIRELESS AUTOMATED ANIMAL MONITORING SYSTEM CALIFORNIA INSTITUTE OF TECHNOLOGY 2024-05-09 US claimed
US-11666216-B2 Wireless automated animal monitoring system CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-06-06 US claimed
CN-111257490-B Method for simultaneously detecting contents of 13 substances in tobacco leaves 沈阳农业大学 2022-09-20 CN claimed
CN-111257490-A Method for simultaneously detecting contents of 13 substances in tobacco leaves 沈阳农业大学 2020-06-09 CN claimed
EP-3629714-A1 WIRELESS AUTOMATED ANIMAL MONITORING SYSTEM California Institute of Technology (US) 2020-04-08 EP claimed
WO-2018217952-A1 WIRELESS AUTOMATED ANIMAL MONITORING SYSTEM CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2018-11-29 WO claimed
US-20180338681-A1 WIRELESS AUTOMATED ANIMAL MONITORING SYSTEM CALIFORNIA INSTITUTE OF TECHNOLOGY 2018-11-29 US claimed
US-20100240070-A1 Nonseparation Assay Methods Using Peroxide Generating Enzymes BECKMAN COULTER, INC. (US) 2010-09-23 US claimed
WO-2009062027-A1 NONSEPARATION ASSAY METHODS USING PEROXIDE GENERATING ENZYMES BECKMAN COULTER, INC. (US) 2009-05-14 WO claimed
EP-1581044-B1 EDIBLE, CHEWABLE OBJECT FOR CARNIVOROUS PETS AND METHOD OF CONTROLLING THE HYGIENE OF THE ORAL CAVITY OF SAID ANIMALS, USING ONE SUCH OBJECT VIRBAC (FR) 2008-11-05 EP claimed
WO-2008124749-A1 ACRIDINIUM PHENYL ESTERS USEFUL IN THE ANALYSIS OF BIOLOGICAL SAMPLES ABBOTT LABORATORIES (US) 2008-10-16 WO claimed
US-20260117236-A1 METHODS AND COMPOSITIONS FOR MODULATING TRICHOME DENSITY AND FLAVOR MOLECULE SECRETION ALTRIA CLIENT SERVICES LLC (US) 2026-04-30 US disclosed
US-12577573-B2 Synthetic production of single-stranded adeno associated viral DNA vectors GENERATION BIO CO. (US) 2026-03-17 US disclosed
US-20260069715-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF HUNTINGTONS DISEASE BY EDITING THE MUTANT HUNTINGTIN GENE LifeEDIT Therapeutics, Inc. (US) 2026-03-12 US disclosed
EP-4695394-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF HUNTINGTON'S DISEASE BY EDITING THE MUTANT HUNTINGTIN GENE Life Edit Therapeutics, Inc. (US) 2026-02-18 EP disclosed
US-4151848-A Tobacco with reduced nicotine content due to microbial treatment BROWN & WILLIAMSON TOBACCO CORPORATION (US) 1979-05-01 US disclosed
US-4140136-A 3-SUCCINOYLPYRIDINE BY-PRODUCT BROWN & WILLIAMSON TOBACCO CORPORATION (US) 1979-02-20 US disclosed
US-4038993-A 3-SUCCINOYL PYRIDINE BROWN & WILLIAMSON TOBACCO CORPORATION (US) 1977-08-02 US disclosed
US-4037609-A FORMING 3-SUCCINOYL-PYRIDINE BROWN & WILLIAMSON TOBACCO CORPORATION (US) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577573-B2 Synthetic production of single-stranded adeno associated viral DNA vectors PHAX, HARS1, VEGFA ALDH1A1 1900/4885CHRNA7 2045/4885CHRNB2 1797/4885
US-20260069715-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF HUNTINGTONS DISEASE BY EDITING THE MUTANT HUNTINGTIN GENE HTT, PRNP, ATXN2L ALDH1A1 3771/4885CHRNA7 977/4885CHRNB2 462/4885
US-20260117236-A1 METHODS AND COMPOSITIONS FOR MODULATING TRICHOME DENSITY AND FLAVOR MOLECULE SECRETION TAS2R50, TAS2R30, TAS2R31 ALDH1A1 3954/4885CHRNA7 1011/4885CHRNB2 262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.