Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779695 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KMT2ASMN1; SMN2LMNAPOLB | |
| SCHEMBL23716956 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KMT2ASMN1; SMN2LMNAPOLB | |
| SCHEMBL19207389 | 0.73 | ALDH1A1 (0.44) | ALDH1A1KMT2ALMNAPOLBMAPK1 | |
| SCHEMBL28194894 | 0.68 | NPSR1 (0.47) | ALDH1A1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL28026626 | 0.68 | ALDH1A1 (0.42) | ALDH1A1KMT2ASMN1; SMN2LMNAHTT | |
| Hydrochloric Acid SCHEMBL19858822 | 0.67 | HSD17B10 (0.37) | ALDH1A1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL3964785 | 0.67 | ALDH1A1 (0.45) | ALDH1A1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL307698 | 0.65 | OPRK1 (0.47) | KMT2ALMNAHTTPOLBPHGDH | |
| SCHEMBL6799570 | 0.65 | SMN1; SMN2 (0.35) | ALDH1A1KMT2ASMN1; SMN2LMNAHTT | |
| Hydrochloric Acid SCHEMBL7563191 | 0.64 | MAPT (0.43) | ALDH1A1KMT2ASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163697-A1 | Multicomponent coupling and glycopeptide synthesis with cyclic thioanhydrides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163697-A1 | Multicomponent coupling and glycopeptide synthesis with cyclic thioanhydrides | LNPEP, CLSPN, GALNT14 | ALDH1A1 4243/4885KMT2A 4163/4885SMN1; SMN2 4369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.