SCHEMBL4183069

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4188131	0.82	HSP90AB1 (0.39)	HSP90AB1ALDH1A1GAAGFERDRD2
	SCHEMBL9340684	0.82	SLC7A5 (0.49)	HSP90AB1ALDH1A1GAAGFERDRD2
	SCHEMBL4184054	0.81	HSP90AB1 (0.38)	HSP90AB1ALDH1A1GAAGFERDRD2
	SCHEMBL3839217	0.81	CYP4F2 (0.50)	HSP90AB1ALDH1A1GAAGFERDRD2
	SCHEMBL2977953	0.80	HSP90AB1 (0.76)	HSP90AB1ALDH1A1GAAGFERCYP4F2
	SCHEMBL1525541	0.79	HSP90AB1 (0.52)	HSP90AB1ALDH1A1GAAGFERNPC1
	SCHEMBL27742563	0.78	ALDH1A1 (0.40)	HSP90AB1ALDH1A1DRD2PREPCALM1
	SCHEMBL8151711	0.78	HSP90AB1 (0.92)	HSP90AB1ALDH1A1GAAGFERNPC1
	SCHEMBL478058	0.78	HSP90AB1 (1.00)	HSP90AB1ALDH1A1GAAGFERNPC1
	SCHEMBL9202392	0.76	HSP90AB1 (0.69)	HSP90AB1ALDH1A1GAAGFERNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.