Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.72 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | UGCG | Q16739 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599045 | 1.00 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2MAPTCERT1 | |
| SCHEMBL16714723 | 1.00 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2MAPTCERT1 | |
| SCHEMBL4139305 | 1.00 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2MAPTCERT1 | |
| SCHEMBL12215278 | 1.00 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2MAPTCERT1 | |
| SCHEMBL4139311 | 1.00 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2MAPTCERT1 | |
| SCHEMBL9472620 | 1.00 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2MAPTCERT1 | |
| SCHEMBL11857445 | 0.92 | SOAT2 (0.64) | ALDH1A1ASAH1ACER2MAPTFAAH | |
| SCHEMBL11857434 | 0.92 | SOAT2 (0.64) | ALDH1A1ASAH1ACER2MAPTFAAH | |
| SCHEMBL11396580 | 0.91 | ALDH1A1 (0.61) | ALDH1A1ASAH1ACER2MAPTCERT1 | |
| Melinamide SCHEMBL1650618 | 0.89 | EPHX2 (0.62) | ALDH1A1ASAH1ACER2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086835-A1 | NOVEL CYANOGUANIDINES | TOPOTARGET A/S (DK) | 2009-07-16 | — | — | WO | disclosed |