Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183388 | 1.00 | GPR119 (0.48) | GPR119NAMPTCCNA2CDK2 | |
| SCHEMBL4168857 | 0.82 | GPR119 (0.49) | GPR119NAMPT | |
| SCHEMBL4168862 | 0.82 | GPR119 (0.49) | GPR119NAMPT | |
| SCHEMBL4166576 | 0.80 | GPR119 (0.52) | GPR119NAMPT | |
| SCHEMBL4166579 | 0.80 | GPR119 (0.52) | GPR119NAMPT | |
| SCHEMBL1532752 | 0.78 | GPR119 (0.55) | GPR119 | |
| SCHEMBL1532755 | 0.78 | GPR119 (0.55) | GPR119 | |
| SCHEMBL387315 | 0.77 | GPR119 (0.48) | GPR119NAMPT | |
| SCHEMBL392253 | 0.77 | GPR119 (0.47) | GPR119NAMPT | |
| SCHEMBL4168335 | 0.75 | GPR119 (0.46) | GPR119NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193359-B2 | G-protein coupled receptor agonists | PROSIDION LIMITED (GB) | 2012-06-05 | — | — | US | disclosed |
| US-20090099227-A1 | G-Protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099227-A1 | G-Protein Coupled Receptor Agonists | GPR119, GPR65, GPR84 | GPR119 1/4885NAMPT 1742/4885CCNA2 4430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.