Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 5/20 | 0.35 |
| ▸ | CES2 | O00748 | 5/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11354924 | 0.85 | CES2 (0.38) | ALDH1A1TP53CES1CES2GMNN | |
| SCHEMBL4630334 | 0.81 | EPHX1 (0.39) | ALDH1A1NPSR1TP53CES1CES2 | |
| SCHEMBL8207874 | 0.79 | — | — | |
| SCHEMBL11488088 | 0.79 | — | — | |
| SCHEMBL946019 | 0.77 | — | — | |
| SCHEMBL11862243 | 0.77 | MEN1 (0.39) | ALDH1A1NPSR1TP53CES1CES2 | |
| SCHEMBL11149120 | 0.76 | EPHX1 (0.35) | ALDH1A1NPSR1TP53CES1CES2 | |
| SCHEMBL11293412 | 0.76 | CES2 (0.45) | ALDH1A1TP53CES1CES2GMNN | |
| SCHEMBL11722997 | 0.76 | CES1 (0.38) | ALDH1A1NPSR1TP53CES1CES2 | |
| SCHEMBL28509051 | 0.76 | CASP2 (0.45) | ALDH1A1NPSR1TP53CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209480-A1 | CENTRAL ADMINISTRATION OF STABLE FORMULATIONS OF THERAPEUTIC AGENTS FOR CNS CONDITIONS | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-08-20 | — | — | US | disclosed |
| EP-0928340-A1 | INVASION-INDUCING AGENTS AND INVASION-INHIBITORS FOR USE IN WOUND HEALING AND CANCER | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-07-14 | — | — | EP | disclosed |
| WO-1998022617-A1 | INVASION-INDUCING AGENTS AND INVASION-INHIBITORS FOR USE IN WOUND HEALING AND CANCER | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209480-A1 | CENTRAL ADMINISTRATION OF STABLE FORMULATIONS OF THERAPEUTIC AGENTS FOR CNS CONDITIONS | INA, BDNF, PMP22 | ALDH1A1 2618/4885NPSR1 370/4885TP53 4318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.