SCHEMBL4184319

SCHEMBL4184319

C[C@@H](CC1CCCCC1)N(Cc1ccccc1NS(=O)(=O)c1ccc2c(c1)CCN(C(=O)C(F)(F)F)C2)OC(=O)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MOGAT2 Q3SYC2 18/20 0.43
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL4184322 0.91 ESR1 (0.42) MOGAT2ESR1ESR2LMNATP53
SCHEMBL4200117 0.85 TSHR (0.40) MOGAT2LMNATP53MAPTTHRB
SCHEMBL4195078 0.84 ALDH1A1 (0.39) MOGAT2LMNATP53MAPTTHRB
SCHEMBL4186009 0.83 MOGAT2 (0.47) MOGAT2ESR1ESR2LMNATP53
SCHEMBL4184464 0.82 MOGAT2 (0.47) MOGAT2ESR1ESR2LMNATP53
SCHEMBL14343600 0.81 MOGAT2 (0.43) MOGAT2ESR1ESR2LMNATP53
SCHEMBL4197642 0.80 MOGAT2 (0.43) MOGAT2ESR1ESR2LMNATP53
Cyclohexane SCHEMBL4193643 0.78 ESR1 (0.46) MOGAT2ESR1ESR2LMNATP53
Cyclopentane SCHEMBL4198281 0.78 ESR1 (0.46) MOGAT2ESR1ESR2LMNATP53
Cyclohexanol SCHEMBL4191255 0.78 MOGAT2 (0.44) MOGAT2ESR1ESR2LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 MOGAT2 3660/4885ESR1 1212/4885ESR2 714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.