Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | LDHB | P07195 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268292 | 0.83 | CYP3A4 (0.50) | CYP3A4CSNK2A1ACHEALDH1A1LDHA | |
| SCHEMBL841683 | 0.83 | CYP3A4 (0.45) | CYP3A4CSNK2A1ACHEALDH1A1LDHA | |
| SCHEMBL14156171 | 0.82 | CYP3A4 (0.54) | CYP3A4CSNK2A1ACHEALDH1A1LDHA | |
| SCHEMBL31335714 | 0.82 | CYP3A4 (0.54) | CYP3A4CSNK2A1ACHEALDH1A1LDHA | |
| SCHEMBL14989172 | 0.82 | KDM4E (0.47) | CYP3A4CSNK2A1ACHEALDH1A1LDHA | |
| SCHEMBL31373145 | 0.82 | KDM4E (0.47) | CYP3A4CSNK2A1ACHEALDH1A1LDHA | |
| SCHEMBL756616 | 0.81 | KDM4E (0.45) | CYP3A4CSNK2A1ACHEALDH1A1LDHA | |
| SCHEMBL10663487 | 0.80 | KDM4E (0.44) | CYP3A4CSNK2A1ACHEALDH1A1LDHA | |
| SCHEMBL11083912 | 0.80 | THRB (0.48) | CSNK2A1ALDH1A1MYCMCL1KDM4E | |
| SCHEMBL28669355 | 0.80 | CYP3A4 (0.57) | CYP3A4ACHEALDH1A1LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032733-B | Fluorine-containing ether compound, fluorine-containing ether composition, coating liquid, article, and method for producing same | ＡＧＣ株式会社 | 2022-06-21 | — | — | CN | disclosed |
| CN-111032733-A | Fluorine-containing ether compound, fluorine-containing ether composition, coating liquid, article, and method for producing same | ＡＧＣ株式会社 | 2020-04-17 | — | — | CN | disclosed |
| US-20150087601-A1 | POLYMER MICELLE COMPLEX INCLUDING NUCLEIC ACID | THE UNIVERSITY OF TOKYO (JP) | 2015-03-26 | — | — | US | disclosed |
| US-20130216480-A1 | AMPHIPHILIC POLYMERS AND METHODS OF USE THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-08-22 | — | — | US | disclosed |
| US-8349991-B2 | Amphiphilic polymers and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-01-08 | — | — | US | disclosed |
| US-20090018216-A1 | POLYMER MICELLE COMPLEX INCLUDING NUCLEIC ACID | THE UNIVERSITY OF TOKYO (JP) | 2009-01-15 | — | — | US | disclosed |
| EP-1879626-A2 | AMPHIPHILIC POLYMERS AND METHODS OF USE THEREOF | Massachusetts Institute of Technology (US) | 2008-01-23 | — | — | EP | disclosed |
| US-20060269479-A1 | Amphiphilic polymers and methods of use thereof | UNIVERSITY OF MASSACHUSETTS LOWELL | 2006-11-30 | — | — | US | disclosed |
| WO-2006113666-A2 | AMPHIPHILIC POLYMERS AND METHODS OF USE THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060269479-A1 | Amphiphilic polymers and methods of use thereof | ABCB4, ANXA3, ANXA5 | CYP3A4 4749/4885CSNK2A1 4641/4885ACHE 4047/4885 |
| US-20150087601-A1 | POLYMER MICELLE COMPLEX INCLUDING NUCLEIC ACID | XRCC6, XRCC5, TLR9 | CYP3A4 4786/4885CSNK2A1 490/4885ACHE 4734/4885 |
| US-20130216480-A1 | AMPHIPHILIC POLYMERS AND METHODS OF USE THEREOF | ABCB4, ANXA3, ANXA5 | CYP3A4 4749/4885CSNK2A1 4641/4885ACHE 4047/4885 |
| US-20090018216-A1 | POLYMER MICELLE COMPLEX INCLUDING NUCLEIC ACID | XRCC6, XRCC5, TLR9 | CYP3A4 4786/4885CSNK2A1 490/4885ACHE 4734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.