SCHEMBL4184563

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4173776	0.90	CBFB (0.64)	CBFBTRPV1DGAT1KCNH2NPBWR1
	SCHEMBL4182134	0.89	CBFB (0.55)	CBFBTRPV1DGAT1KCNH2NPBWR1
	SCHEMBL904706	0.88	TRPV1 (0.61)	CBFBTRPV1DGAT1KCNH2NPBWR1
	SCHEMBL4189155	0.88	CBFB (0.53)	CBFBTRPV1DGAT1KCNH2NPBWR1
	SCHEMBL4190228	0.85	DHODH (0.44)	CBFBTRPV1MAPK13RAF1MAPK12
	SCHEMBL4552457	0.83	NPBWR1 (0.44)	CBFBDGAT1KCNH2NPBWR1RIPK1
	SCHEMBL4193994	0.83	CBFB (0.47)	CBFBTRPV1DGAT1KCNH2NPBWR1
	SCHEMBL4184778	0.82	CBFB (0.47)	CBFBTRPV1
	SCHEMBL4174495	0.81	CBFB (0.61)	CBFBTRPV1DGAT1KCNH2KDM4E
	SCHEMBL4189702	0.81	TRPV1 (0.67)	CBFBTRPV1DGAT1KCNH2NPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.