Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CRHR1 | P34998 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12724987 | 0.87 | HPGD (0.51) | HPGDALDH1A1POLBKDM4ETAS1R3 | |
| SCHEMBL13493618 | 0.81 | KDM1A (0.57) | HPGDALDH1A1POLBKDM4EHTT | |
| SCHEMBL9967851 | 0.81 | RAB9A (0.48) | HPGDALDH1A1GAA | |
| SCHEMBL4191547 | 0.81 | HPGD (0.71) | HPGDALDH1A1POLBACKR3SMYD3 | |
| SCHEMBL28188798 | 0.78 | GAA (0.57) | HPGDALDH1A1KDM4EHTTRXFP1 | |
| SCHEMBL3343302 | 0.78 | HPGD (0.55) | HPGDALDH1A1HTTGAATAS1R3 | |
| SCHEMBL7987541 | 0.78 | CRBN (0.60) | HPGDALDH1A1POLBKDM4ETAS1R3 | |
| SCHEMBL10282411 | 0.78 | TAS1R3 (0.62) | HPGDALDH1A1POLBTAS1R3TAS1R1 | |
| SCHEMBL31567826 | 0.78 | CRBN (0.60) | HPGDALDH1A1POLBKDM4ETAS1R3 | |
| SCHEMBL3225623 | 0.78 | HPGD (0.55) | HPGDALDH1A1POLBKDM4ETAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRM1, GRIN1, GRM2 | HPGD 2246/4885CRHR1 372/4885ALDH1A1 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.